Roxithromycin
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Roxithromycin 속성
- 녹는점
- 111-118?C
- 알파
- D25 -77.5 ±2° (c = 0.45 in chloroform)
- 끓는 점
- 864.7±75.0 °C(Predicted)
- 밀도
- 1.25±0.1 g/cm3(Predicted)
- 인화점
- >110°(230°F)
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- 클로로포름: 가용성10mg/mL
- 산도 계수 (pKa)
- pKa 9.27±0.01(H2O t = 25.0 I = 0.15 (KCl)) (Uncertain)
- 물리적 상태
- 가루
- 수용성
- 수용성 18µg/ml
- Merck
- 14,8276
- InChIKey
- RXZBMPWDPOLZGW-HEWSMUCTSA-N
- CAS 데이터베이스
- 80214-83-1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Roxithromycin C화학적 특성, 용도, 생산
개요
Roxithromycin, an oxime ether derivative of erythromycin, is a new macrolide antibiotic of high potency and long duration. Its in v i m activity spectrum is similar to that of erythromycin, but is superior to the latter against Legionella, Mycoplasma and Chlamydia.화학적 성질
White Solid용도
Roxithromycin was one of the new generation erythromycins introduced in the 1980s. Improved acid stability was achieved by converting the 9-keto group to the more stable oxime and alkylation of the oxime to provide the methoxyethoxymethyl ether oxime. In vivo, roxithromycin exhibits higher tissue levels and a longer half-life while being slightly less potent than erythromycin in vitro.Antimicrobial activity
Activity against common pathogens is comparable to that of erythromycin. It is active against L. monocytogenes, C. jejuni, H. ducreyi, G. vaginalis, Bord. pertussis, C. diphtheriae, B. burgdorferi, H. pylori, the M. avium complex, Chlamydia spp., and U. urealyticum.Pharmaceutical Applications
A semisynthetic derivative of erythromycin A formulated for oral use.부작용
It is generally well tolerated, adverse effects being described in 3–4% of patients, mostly gastrointestinal disturbance (abdominal pain, nausea and diarrhea). Headache, weakness, dizziness, rash and reversible changes in liver function tests and increased eosinophils and platelets have also been described.Roxithromycin 준비 용품 및 원자재
원자재
준비 용품
Roxithromycin 공급 업체
글로벌( 568)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 893 | 58 |
| Henan Suikang Pharmaceutical Co.,Ltd. | +8618239973690 |
sales@suikangpharm.com | China | 178 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
Roxithromycin 관련 검색:
에리트로마이신 5-히드록시펜탄알 옥심
Dirithromycin
2-Methoxyethoxymethyl chloride
Glycerol 5-hydroxydecanoate
ERYTHROMYCIN OXIME
N-DEMETHYLROXITHROMYCIN
ROXITHROMYCIN FOR SYSTEM SUITABILITY
ROXITHROMYCIN LACTOBIONATE
Roxithromycin
2-METHYLVALERALDEHYDE OXIME
ROXITHROMYCIN DISPERSIBLE TABLETS
ROXITHROMYCIN EPR(CRM STANDARD)
ROXITHROMYCIN DIHYDRATE
ROXITHROMYCIN FOR SYSTEM SUITABILITY EPY(CRM STANDARD)
Roxithromycin EP2001/JP93/CP2000
Roxithromycin granules
Roxithromycin Tablets