N-Boc-4-피페리딘메탄올
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N-Boc-4-피페리딘메탄올 속성
- 녹는점
- 78-82 °C (lit.)
- 끓는 점
- 308.0±15.0 °C(Predicted)
- 밀도
- 1.059±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 메탄올에 용해됨
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 14.94±0.10(Predicted)
- 색상
- 흰색에서 갈색으로
- InChI
- InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
- InChIKey
- CTEDVGRUGMPBHE-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(CO)CC1
- CAS 데이터베이스
- 123855-51-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
N-Boc-4-피페리딘메탄올 C화학적 특성, 용도, 생산
화학적 성질
White to light brown solid용도
N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.
주요 응용
N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.일반 설명
N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.N-Boc-4-피페리딘메탄올 준비 용품 및 원자재
원자재
준비 용품
N-Boc-4-피페리딘메탄올 공급 업체
글로벌( 489)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Siyang Liaoning Biochemical Products Co. Ltd | +86-15221114306; +8615221114306 |
2594582574@qq.com | China | 574 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 |
sales1@hbganmiao.com | China | 253 | 58 |
Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +8615064153060 |
sales01@jndxj.com | China | 291 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
Zjartschem | +86-571 87238903 |
jocelynpan@zjarts.com | CHINA | 993 | 58 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 341 | 58 |
Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |
N-Boc-4-피페리딘메탄올 관련 검색:
삼차부틸 아세트산 터트-부틸 퍼옥시아세테이트 tert-부틸알코올 드로페리돌, 펜타닐 할로페리돌 2,2,6,6-사메틸-4-피페리디놀
N-(tert-Butoxycarbonyl)-4-piperidone
N-Boc-Piperidine-4-carboxylic acid methyl ester
PHENCYCLIDINE-D5 HYDROCHLORIDE
4-Piperidinemethanol
1-Boc-2-piperidinemethanol,1-N-Boc-2-piperidinemethanol,1-TERT-BUTOXYCARBONYL-2-PIPERIDINEMETHANOL, N-BOC-2-PIPERIDINEMETHANOL
1-TERT-BUTOXYCARBONYL-3-PIPERIDINEMETHANOL, N-BOC-3-PIPERIDINEMETHANOL,1-Boc-3-piperidinemethanol
1-Boc-4-(2-hydroxyethyl)piperidine
N-BOC-4-Hydroxypiperidine
tert-Butyl 4-methylenepiperidine-1-carboxylate
1-Boc-4-cyanopiperidine
N-Boc-(2R,3R,4S)-dolaproine
TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE