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LY 223982

LY 223982 구조식 이미지

카스 번호:: 117423-74-2

상품명:: LY 223982

동의어(영문):: CGS23131;LY 223982;SKF107324);LY223982,LY-223982;LY223982 Exclusive;SYZSSLLFRVDRHL-QPJJXVBHSA-N;LY223982 (Synonyms: CGS23131;5-(3-Carboxybenzoyl)-2-[(E)-6-(4-methoxyphenyl)-5-hexenyloxy]benzenepropanoic acid;Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-

CBNumber:: CB21341434

분자식:: C30H30O7

포뮬러 무게:: 502.55

MOL 파일:: 117423-74-2.mol

속성

안전

용도

공급 업체 35

LY 223982 속성

녹는점: 151-152 °C

끓는 점: 753.8±60.0 °C(Predicted)

밀도: 1.235±0.06 g/cm3(Predicted)

저장 조건: -20°C Freezer

용해도: 클로로포름(약간 용해됨, 가열, 초음파 처리), DMSO(아주 적은 양으로 녹여라)

물리적 상태: 결정성 고체

산도 계수 (pKa): 3.81±0.10(Predicted)

안전

LY 223982 C화학적 특성, 용도, 생산

개요

Leukotriene B₄ (LTB₄) is a dihydroxy fatty acid derived from the 5-lipoxygenase pathway of arachidonic acid metabolism and is an important mediator of the inflammatory process. The benzophenone dicarboxylic acid derivative LY223982 is a potent BLT₁ receptor antagonist. It inhibits the specific binding of radiolabeled-LTB₄ to isolated human neutrophils with an IC₅₀ value of 13.2 nM. LY223982 inhibits the leukotriene B₄ (LTB₄)-induced aggregation of guinea pig and human neutrophils with IC₅₀ values of 74 and 100 nM, respectively. However, concentrations of LY223982 up to 10 μM do not inhibit binding of LTB₄ to human BLT₁ or BLT₂ expressed in CHO cells.

용도

LY223982 is a potent P2Y7 (BLT1) receptor antagonist.

LY 223982 준비 용품 및 원자재

원자재

준비 용품

LY 223982 공급 업체

글로벌( 35)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3421	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Angel Pharmatech, Ltd.	17317130613	3358272972@qq.com	China	3238	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58

LY 223982 관련 검색:

LY 223982 3-(3-FORMYLPHENYL)PROPANOIC ACID METHOXYPHENONE 4-METHOXY-3'-METHYLBENZOPHENONE 3-(2-METHOXYPHENYL)PROPIONIC ACID