노페네프린

노페네프린
노페네프린 구조식 이미지
카스 번호:
536-21-0
한글명:
노페네프린
동의어(한글):
노페네프린
상품명:
norfenefrine
동의어(영문):
Normetol;Normezaton;Metacardiol;Brn 1211018;norfenefrine;m-Octopamine;Metaoctopamine;DL-m-Octopamine;NORFENEFRINEBASE;Normetasympathol
CBNumber:
CB2902175
분자식:
C8H11NO2
포뮬러 무게:
153.18
MOL 파일:
536-21-0.mol

노페네프린 속성

녹는점
75-77 °C
끓는 점
276.1°C (rough estimate)
밀도
1.1577 (rough estimate)
굴절률
1.5010 (estimate)
산도 계수 (pKa)
pKa 8.67(H2O,t undefined,I undefined) (Uncertain)

안전

독성 LD50 oral in rat: 390mg/kg

노페네프린 C화학적 특성, 용도, 생산

Originator

Zordel,Grelan,Japan,1970

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

노페네프린 준비 용품 및 원자재

원자재

준비 용품


노페네프린 공급 업체

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