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norfenefrine

norfenefrine Structure
norfenefrine structure
CAS No.
536-21-0
Chemical Name:
norfenefrine
Synonyms
Normetol;Normezaton;Metacardiol;Brn 1211018;norfenefrine;m-Octopamine;Metaoctopamine;DL-m-Octopamine;NORFENEFRINEBASE;Normetasympathol
CBNumber:
CB2902175
Molecular Formula:
C8H11NO2
Molecular Weight:
153.18
MDL Number:
MFCD00215852
MOL File:
536-21-0.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:39
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norfenefrine Properties

Melting point 75-77 °C
Boiling point 276.1°C (rough estimate)
Density 1.1577 (rough estimate)
refractive index 1.5010 (estimate)
pka pKa 8.67(H2O,t undefined,I undefined) (Uncertain)
EWG's Food Scores 1
FDA UNII D2P3M6SRN5
ATC code C01CA05

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in rat: 390mg/kg

norfenefrine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0015836 3-(2-AMINO-1-HYDROXYETHYL)PHENOL 95.00% 536-21-0 0.5G $605 2021-12-16 Buy
Product number Packaging Price Buy
API0015836 0.5G $605 Buy

norfenefrine Chemical Properties,Uses,Production

Originator

Zordel,Grelan,Japan,1970

Definition

ChEBI: Norfenefrine is a member of phenols.

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

norfenefrine synthesis

100-83-4
536-21-0
Synthesis of norfenefrine from 3-Hydroxybenzaldehyde

norfenefrine Preparation Products And Raw materials

Raw materials

Hexamethylenetetramine Hydrogen Sodium iodide 3'-Acetoxyacetophenone Benzenemethanol, 3-hydroxy-α-(nitromethyl)-
1-(2-aMino-3-hydroxyphenyl)ethanone Phenol, 3-(8-nonen-1-yl)- APLPHA-BROMO-M-BENZOYLOXYACETOPHENONE m-vinylphenol 2-Bromo-3′-hydroxyacetophenone
3-HYDROXYM AND ELONITRILE 3-Hydroxybenzaldehyde

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Preparation Products

norfenefrine Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671 sales@tnjchem.com China 34572 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Bejing Famous Pharmaceutical Technology Co., Ltd. 13331045123 1963319514@qq.com China 14234 58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd. 027-51831887 15337167856 hubeixinyuanshun@163.com China 10305 58
Shandong Wadesen Biotechnology Co. LTD 0531-88723173 18596073690 1047208234@qq.com China 3447 58
Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd 02783850058 15377551550 whhdyxchem027@sina.com China 2442 58
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
ChemStrong Scientific Co.,Ltd 56
Bejing Famous Pharmaceutical Technology Co., Ltd. 58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd. 58
Shandong Wadesen Biotechnology Co. LTD 58
Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd 58

536-21-0(norfenefrine)Related Search:

DL-ADRENALINE HYDROCHLORIDE Levisoprenaline Norfenefrine hydrochloride DL-NORADRENALINE HYDROCHLORIDE (+)-Bicuculline
Phenylephrine hydrochloride Isoprenaline hydrochloride L-NORADRENALINE BITARTRATE L-ADRENALINE BITARTRATE (-)-BICUCULLINE METHOBROMIDE
Isoprenaline sulphate (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Norepinephrine DL-Adrenalin Phenylephrine
(S)-(+)-ISOPROTERENOL L(+)-BITARTRATE Octopamine DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE

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norfenefrine NORFENEFRINEBASE (+-)-m-Octopamine (+-)-Norphenylephrine 1-(3-Hydroxyphenyl)-2-aminoethanol 1-(m-Hydroxyphenyl)-2-aminoethanol a-(Aminomethyl)-m-hydroxybenzyl alcohol Benzenemethanol, a-(aminomethyl)-3-hydroxy- (9CI) Benzyl alcohol, a-(aminomethyl)-m-hydroxy- (6CI, 8CI) DL-1-(3-Hydroxyphenyl)-2-aminoethanol dl-1-(m-Hydroxyphenyl)-2-aminoethanol DL-m-Octopamine DL-Norphenylephrine Metacardiol Metaoctopamine m-Hydroxyphenylethanolamine m-Octopamine Normetasympathol Normetasynephrine Normetol Normezaton p-Hydroxynoradrenaline rac-(R*)-2-Amino-1-(3-hydroxyphenyl)ethanol 1-(3-Hydroxyphenyl)-1-hydroxy-2-aminoethane 4779-94-6 (Hydrochloride) alpha-(Aminomethyl)-m-hydroxybenzyl alcohol Benzyl alcohol, alpha-(aminomethyl)-m-hydroxy- Brn 1211018 Einecs 208-626-8 alpha-(AMinoMethyl)-3-hydroxybenzeneMethanol Benzenemethanol, α-(aminomethyl)-3-hydroxy- Norfenefrine Impurity A Etilefrine hydrochloride EP Impurity C 536-21-0