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PHENSUXIMIDE

PHENSUXIMIDE 구조식 이미지

카스 번호:: 86-34-0

상품명:: PHENSUXIMIDE

동의어(영문):: pm334;Lifen;Epimid;Lifene;PM 334;Epimal;Mirotin;Milontin;Milonton;Mirontin

CBNumber:: CB3480203

분자식:: C11H11NO2

포뮬러 무게:: 189.21

MOL 파일:: 86-34-0.mol

속성

안전

용도

공급 업체 53

PHENSUXIMIDE 속성

녹는점: 71-73°

끓는 점: 324.47°C (rough estimate)

밀도: 1.1596 (rough estimate)

굴절률: 1.5012 (estimate)

저장 조건: Refrigerator

용해도: 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): -1.86±0.40(Predicted)

색상: 흰색에서 황백색까지

수용성: 4.2g/L(25℃)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2925190100
독성	LD50 orally in mice: 960 mg/kg (Chen, Ensor)

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501

예방조치문구:

NFPA 704

	0
1		0

PHENSUXIMIDE C화학적 특성, 용도, 생산

개요

Phensuximide is an anticonvulsant. It inhibits seizures induced by maximal electroshock (MES) and pentylenetetrazole in mice (ED₅₀s = 112 and 50 mg/kg, respectively). Phensuximide (1.25 mmol/kg, i.p.) induces proteinuria and hematuria in rats. Formulations containing phensuximide have been used in the treatment of petit mal seizures.

용도

Phensuximide, like ethosuximide, is an anticonvulsant drug used in minor forms of epilepsy.

Clinical Use

Phensuximide occasionally is used for the treatment of absence seizures refractory to other drugs, although it is considered to be less effective than ethosuximide. It is excreted in both urine and bile, and it may cause harmless pink to red discoloration of the urine. It should be used with caution in patients with acute intermittent porphyria.

Purification Methods

Crystallise phensuximide from hot 95% EtOH (m 72-73o). At 25o 1g of the imide dissolves in 1g of *C6H6, 18g of Et2O, 9.5g of EtOH, 5.1g of MeOH and 235g of H2O. [Beilstein 21 II 300, 21 III/IV 5465.]

PHENSUXIMIDE 준비 용품 및 원자재

원자재

아세틸 염화물 DL-Phenylsuccinic acid (R)-2-phenylbutane-1,4-diol Phenylmaleic anhydride N-Methylmaleimide 2-(Dimethylphenylsilyl)benzyl alcohol 페닐붕산 아닐린 메틸아민 벤조산 페닐아세토나이트릴

준비 용품

1-Methyl-3-phenyl-1H-pyrrole-2,5-dione

PHENSUXIMIDE 공급 업체

글로벌( 53)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29067	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9116	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Sinopharm Chemical Reagent Co,Ltd.	86-21-63210123	sj_scrc@sinopharm.com	China	9823	79
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12338	58
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 18112977050	cb6@aikonchem.com	China	16687	50

PHENSUXIMIDE 관련 검색:

METHSUXIMIDE PHENSUXIMIDE suclofenide 2,5-Pyrrolidinedione, 3-(4-chlorophenyl)-1-(3-methyl-2-pyridinyl)- PB 601 3,5-dibromophenylsuccinic acid N-methylimide 3-(3-Chlorophenyl)-1-(3-methyl-2-pyridinyl)-2,5-pyrrolidinedione 2,5-Pyrrolidinedione, 1-(2-(dimethylamino)ethyl)-3-phenyl-, monohydroc hloride (9CI) Benzenesulfonamide, 3-(2,5-dioxo-3-methyl-3-phenyl-1-pyrrolidinyl)- 1,2-NAPHTHALENEDICARBOXIMIDE, 1,2,3,4-TETRAHYDRO-N-METHYL- Morsuximide 4-(2,5-Dioxo-3-phenyl-1-pyrrolidinyl)-3-fluorobenzenesulfonamide 2-Chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)benzenesulfonamide 3-(3-Chlorophenyl)-1-(4-methyl-2-pyridinyl)-2,5-pyrrolidinedione 2,5-Pyrrolidinedione, 1-(5-(diethylamino)pentyl)-3-phenyl-, monohydroc hloride (9CI) Benzenesulfonamide, 4-(2,5-dioxo-3-(4-chlorophenyl)-3-methyl-1-pyrroli dinyl)- 2,5-Pyrrolidinedione, 1-(3-(diethylamino)propyl)-3-phenyl-, monohydroc hloride (9CI) 2,5-Pyrrolidinedione, 1-cyclohexyl-3-phenyl-