Silodosin
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Silodosin 속성
- 녹는점
- >104°C (dec.)
- 알파
- D25 -14.0° (c = 1.01 in methanol)
- 끓는 점
- 601.4±55.0 °C(Predicted)
- 밀도
- 1.249±0.06 g/cm3(Predicted)
- 저장 조건
- under inert gas (nitrogen or Argon) at 2–8 °C
- 용해도
- 수성 염기(약간 용해됨, 가열 초음파 처리), DMSO(약간 용해됨, 초음파 처리), 메탄올
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 14.85±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- CAS 데이터베이스
- 160970-54-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| HS 번호 | 29339900 |
|---|
Silodosin C화학적 특성, 용도, 생산
개요
Silodosin, an a1A adrenoceptor (a1A-AR) antagonist selective for prostatic receptors, was launched as an oral treatment for dysuria associated with benign prostatic hypertrophy (BPH). The regulation of smooth muscle tone in the bladder neck and prostate is thought to be primarily mediated by a1A-AR. Blockade of these receptors can cause smooth muscle relaxation in these areas, resulting in improved symptoms and urinary flow rates. Conversely, a1B-AR are largely located on vascular smooth muscle, and antagonism of these receptors can cause tissue relaxation and potentially decrease cardiac compensation mechanisms involved in regulating blood pressure.화학적 성질
White Solid용도
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. It causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes prSilodosin 준비 용품 및 원자재
원자재
tert-butyl (2R)-1-[1-(3-benzyloxypropyl)-7-carbamoyl-indolin-5--yl]propan-2-yl2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylcarbamate
1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile
1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-
준비 용품
Silodosin 공급 업체
글로벌( 406)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 |
erin@hbldbiotech.com | China | 878 | 58 |
| Hebei Dangtong Import and export Co LTD | +8615632927689 |
admin@hbdangtong.com | China | 991 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 902 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
Silodosin 관련 검색:
파라폼알데하이드
1H-Indole-7-carboxamide, 5-[(2R)-2-aminopropyl]-2,3-dihydro-1-(3-hydroxypropyl)-
Silodosin Carboxylic Acid Impurity
Silodosin Glucuronide
5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile
Silodosin
O-Acetyl Silodosin
1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-1-(3-hydroxypropyl)indoline-7-carboxamide(WXG00186)
CalciuM polycarbophil
1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-1H-indole-7-carboxaMide
NCFJJNFEEPMRAQ-XMMPIXPASA-N
1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-
Tamsulosin
Voriconazole
Solifenacin succinate
2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate
VILAZODONE