Cynaroside

Cynaroside 구조식 이미지
카스 번호:
5373-11-5
상품명:
Cynaroside
동의어(영문):
LUTEOLIN-7-O-GLUCOSIDE;luteoloside;PETUNIDIN;LUTEOLIN-7-GLUCOSIDE;Galuteolin;cinaroside;glucoluteolin;Luteolin 7-O-β-D-glucopyranoside;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-;CYNAROSIDE
CBNumber:
CB4369516
분자식:
C21H20O11
포뮬러 무게:
448.38
MOL 파일:
5373-11-5.mol
MSDS 파일:
SDS

Cynaroside 속성

녹는점
256~258℃
저장 조건
Sealed in dry,2-8°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
끓는 점
838.1±65.0 °C(Predicted)
밀도
1.713±0.06 g/cm3(Predicted)
산도 계수 (pKa)
6.10±0.40(Predicted)
색상
노란색에서 매우 어두운 노란색까지
안정성
흡습성
InChIKey
PEFNSGRTCBGNAN-QNDFHXLGSA-N
LogP
-0.090 (est)
CAS 데이터베이스
5373-11-5(CAS DataBase Reference)

안전

위험품 표기 Xi
안전지침서 24/25
WGK 독일 3
RTECS 번호 DJ3009400
HS 번호 29389090

Cynaroside C화학적 특성, 용도, 생산

개요

Luteolin-7-O-glucoside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .

화학적 성질

Off-white powder

용도

Luteolin 7-Glucoside is a strong antioxidant ant radical scavenger. Used in cancer prevention.

정의

ChEBI: A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.

Cynaroside 준비 용품 및 원자재

원자재

준비 용품


Cynaroside 공급 업체

글로벌( 265)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5993 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873
sales@chemdad.com China 39916 58

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