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Vincristine

Vincristine 구조식 이미지
카스 번호:
57-22-7
상품명:
Vincristine
동의어(영문):
LCR;Leucid;Vincosid;Cristovin;Leucristine;VINCRISTINE;Pericristine;Vincristine (free base);Leurocristine (7CI, 8CI);Vincaleukoblastine, 22-oxo-
CBNumber:
CB4375960
분자식:
C46H56N4O10
포뮬러 무게:
824.96
MOL 파일:
57-22-7.mol

Vincristine 속성

녹는점
211-216 ºC
알파
D25 +17°; D25 +26.2° (ethylene chloride)
끓는 점
761.92°C (rough estimate)
밀도
1.1539 (rough estimate)
굴절률
1.6000 (estimate)
산도 계수 (pKa)
5.4(at 25℃)
안정성
Stable, but may be heat sensitive. Incompatible with strong oxidizing agents.
EPA
Vincaleukoblastine, 22-oxo-(57-22-7)

안전

유엔번호(UN No.) 1544
위험 등급 6.1(a)
포장분류 II
유해 물질 데이터 57-22-7(Hazardous Substances Data)
독성 LD50 i.p. in mice: 5.2 mg/kg (Adamson)

Vincristine C화학적 특성, 용도, 생산

화학적 성질

solid

용도

Antineoplastic[Note—Graphic formula same as for Vinblastine Sulfate, except that R is CHO].

상표명

Oncovin (Lilly); Vincasar (Sicor).

일반 설명

A white crystalline solid. Melting point 218°C. Used as an antineoplastic.

건강위험

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

화재위험

Flash point data for Vincristine are not available, but Vincristine is probably combustible.

Clinical Use

Vincristine is an important component of the curative combination chemotherapy for acute lymphoblastic leukemia, Hodgkin’s disease (the MOPP regimen), and non-Hodgkin’s lymphomas. It is also used in several regimens for pediatric solid tumors, including Wilms’ tumor, Ewing’s sarcoma, rhabdomyosarcoma, and neuroblastoma; in adult tumors of the breast, lung, and cervix; and in sarcomas. Its relative lack of myelosuppression makes it more attractive than vinblastine for use in combination with myelotoxic drugs.Vinblastine is especially useful in testicular carcinomas and is also active in Hodgkin’s disease, other types of lymphomas, breast cancer, and renal cell carcinoma.

Vincristine 준비 용품 및 원자재

원자재

준비 용품


Vincristine 공급 업체

글로벌( 112)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 892 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2258 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4001 58
Shaanxi Pioneer Biotech Co., Ltd .
86-13259417953(Whatsapp)
029-84385017 sales@pioneerbiotech.com CHINA 3030 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58

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