METHAPYRILENE HYDROCHLORIDE

METHAPYRILENE HYDROCHLORIDE 구조식 이미지
카스 번호:
135-23-9
상품명:
METHAPYRILENE HYDROCHLORIDE
동의어(영문):
dozar;barhist;coryzol;blueline;capathyn;histafed;methacon;Cohistine;somnicaps;methoxylene
CBNumber:
CB4405690
분자식:
C14H20ClN3S
포뮬러 무게:
297.85
MOL 파일:
135-23-9.mol
MSDS 파일:
SDS

METHAPYRILENE HYDROCHLORIDE 속성

녹는점
162°
저장 조건
room temp
용해도
DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
안정성
흡습성
EPA
Methapyrilene hydrochloride (135-23-9)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 25
안전지침서 22-36-45
유엔번호(UN No.) UN 2811 6.1/PG 3
WGK 독일 3
RTECS 번호 UT1750000
위험 등급 6.1(b)
포장분류 III
독성 LD50 oral in rat: 200mg/kg
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H301 삼키면 유독함 급성 독성 물질 - 경구 구분 3 위험 GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
예방조치문구:
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
NFPA 704
0
2 0

METHAPYRILENE HYDROCHLORIDE C화학적 특성, 용도, 생산

용도

Methapyrilene is used as antihistaminic agent.

정의

ChEBI: A hydrochloride that is the monohydrochloride salt of methapyrilene.

일반 설명

Methapyrilene hydrochloride,2-[[2-(dimethylamino)-ethyl]-2-thienylarnino]pyridine monohydrochloride (Histadyl) is available as the bitter-tasting, white crystalline powder that is soluble in water(1:0.5), in alcohol (1:5), and in chloroform (1:3). Its solutionshave a pH of about 5.5. It differs structurally from tripelennaminein having a 2-thiophene—methylene group in placeof the benzyl group. The thiophene ring is considered isostericwith the benzene ring, and the isosteres exhibit similaractivity. A study of the solid-state conformation of methapyrilenehydrochloride showed that the trans-conformation is preferredfor the two ethylenediamine nitrogen atoms. The Foodand Drug Administration declared methapyrilene a potentialcarcinogen in 1979, and all products containing it have beenrecalled.

공기와 물의 반응

Water soluble.

반응 프로필

METHAPYRILENE HYDROCHLORIDE is light sensitive. Solutions of METHAPYRILENE HYDROCHLORIDE in water, DMSO, 95% ethanol or acetone should be stable for 24 hours under normal lab conditions. . Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas.

화재위험

Flash point data for METHAPYRILENE HYDROCHLORIDE are not available; however, METHAPYRILENE HYDROCHLORIDE is probably combustible.

METHAPYRILENE HYDROCHLORIDE 준비 용품 및 원자재

원자재

준비 용품


METHAPYRILENE HYDROCHLORIDE 공급 업체

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