Benzyl carbamate
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Benzyl carbamate 속성
- 녹는점
- 86-89 °C (lit.)
- 끓는 점
- 273.17°C (rough estimate)
- 밀도
- 1.2023 (rough estimate)
- 굴절률
- 1.5810 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 13.42±0.50(Predicted)
- 물리적 상태
- 분말 또는 플레이크
- 색상
- 미색부터 밝은 베이지까지
- 수용성
- 68.02g/L(37℃)
- BRN
- 1865635
- InChIKey
- PUJDIJCNWFYVJX-UHFFFAOYSA-N
- CAS 데이터베이스
- 621-84-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-36/37/38 | ||
| 안전지침서 | 22-24/25-36-26 | ||
| WGK 독일 | 3 | ||
| HS 번호 | 29242995 |
Benzyl carbamate C화학적 특성, 용도, 생산
화학적 성질
Off-white to light beige powder or flakes, melting point 87-89 ℃. Insoluble in water, soluble in organic solvents such as benzene.용도
Benzyl carbamate is a reagent used for the nucleophilic introduction of an amino-protected group, Benzyl carbamates can be considered as a benzyloxycarbonyl (otherwise known as carbobenzyloxy, Cbz or Z) protecting group for amino groups. It was introduced as a versatile alternative to the ethoxy carbamate group in peptide synthesis.주요 응용
Benzyl carbamate is an intermediate in the synthesis of various pharmaceutical compounds. It can be also used as nondeuterated internal standards for the quantitative analysis of carisoprodol in blood.제조 방법
Benzyl carbamate is prepared by reacting benzyl chloroformate with ammonia. Benzyl chloroformate was slowly added to 5 times the volume of cold ammonia water (relative density 0.90) under vigorous stirring, the reaction mixture was placed at room temperature for 30 minutes, the precipitate was filtered out, washed with water and dried to obtain the finished product of benzyl carbamate.Purification Methods
If it smells of NH3, then dry it in a vacuum desiccator and recrystallise it from 2 volumes of toluene and dry it in a vacuum desiccator again. It forms glistening plates from toluene, and can be recrystallised from H2O [Martell & Herbst J Org Chem 6 878 1941, Carter et al. Org Synth Coll Vol III 168 1955]. [Beilstein 6 IV 2278.]Benzyl carbamate 준비 용품 및 원자재
원자재
준비 용품
Benzyl carbamate 공급 업체
글로벌( 359)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com |
jocelynpan@zjarts.com | CHINA | 993 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
Benzyl carbamate 관련 검색:
벤질벤조에이트 포름산벤질에스테르 벤질 알코올 클로르프로팜 벤질 클로로탄소산 아이사토산 무수물
POLYURETHANE
Carbobenzoxyhydrazide
4-Nitrobenzyl chloroformate
AMINOGUANIDINE HEMISULFATE
Aminoguanidine bicarbonate
Sulfamic acid
2,6-DI-TERT-BUTYLNAPHTHALENE SULFONIC ACID SODIUM SALT
Trimethylstearylammonium Chloride
2,3-Butanediol
Ethylene Glycol Dibutyl Ether
Ethylene dimethacrylate
2,2-Diethoxyethylamine