Florantyrone

Florantyrone 구조식 이미지
카스 번호:
519-95-9
상품명:
Florantyrone
동의어(영문):
Zanchol;florantyrone;γ-Oxo-8-fluoranthenebutyric acid;b-(8-Fluoranthoyl)propionic acid;g-Oxo-8-fluoranthenebutanoic acid;3-(4-PHENYLBENZOYL)PROPIONIC ACID;4-(4-BIPHENYLYL)-4-OXOBUTYRIC ACID;b-(8-Fluoranthyloyl)propionic acid;8-Fluoranthenebutanoic acid, γ-oxo-;g-Fluoranthen-8-yl-g-oxybutyric acid
CBNumber:
CB5239126
분자식:
C20H14O3
포뮬러 무게:
302.32
MOL 파일:
519-95-9.mol

Florantyrone 속성

녹는점
184-187 °C(lit.)
끓는 점
574.2±33.0 °C(Predicted)
밀도
1.367±0.06 g/cm3(Predicted)
CAS 데이터베이스
519-95-9(CAS DataBase Reference)

안전

위험품 표기 T
위험 카페고리 넘버 25
안전지침서 28-45
유엔번호(UN No.) UN 2811 6.1/PG 3
WGK 독일 3
RTECS 번호 DV1761000
유해 물질 데이터 519-95-9(Hazardous Substances Data)

Florantyrone MSDS


Florantyrone

Florantyrone C화학적 특성, 용도, 생산

Originator

Zanchol,Searle,US,1957

Manufacturing Process

50 g of fluoranthene and 26 g of succinic anhydride in 500 cc of nitrobenzene were treated at 0°C to 5°C with 75 g of anhydrous aluminum chloride. The temperature was held at 0°C for 4 hours and then allowed gradually to come to room temperature. The reaction mixture was allowed to stand for 16 hours. The reaction mixture was then worked up. In so doing, the reaction mixture was decomposed with dilute HCl, the nitrobenzene was removed by steam distillation and the residue after filtration was dissolved in hot sodium carbonate solution and filtered free of a small amount of nonacidic material. Precipitation from solution with HCl gave a light yellow product which crystallized from a 50-50 mixture of dioxane alcohol as fine platelets which melted at 192°C to 194°C and showed a neutral equivalent of 308 which corresponds closely to the theoretical value of 302 for β-fluoranthoylpropionic acid.
25 g of the crude acid was dissolved in 100 cc of water containing 13 g of sodium carbonate. On cooling a thick syrup was obtained. On dilution to 1 liter precipitation started and after standing 16 hours, the solid which separated was filtered (filtrate treated as below), suspended in water, acidified with HCl and filtered. Crystallization from alcohol gave a light yellow material melting at 199°C to 200°C and having a neutral equivalent of 303.
The filtrate mentioned above, upon acidification thereof with HCl gave a darker acid which melted over a wide range, but had a neutral equivalent which also corresponds to that of β-fluoranthoylpropionic acid.

Therapeutic Function

Hydrocholeretic

Florantyrone 준비 용품 및 원자재

원자재

준비 용품


Florantyrone 공급 업체

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