3-말레이미도-프록실
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3-말레이미도-프록실 속성
- 녹는점
- 86-91 °C
- 끓는 점
- 407.3±28.0 °C(Predicted)
- 밀도
- 1.285±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO(약간 용해됨), 에틸아세테이트(약간 용해됨)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 4.74±0.10(Predicted)
- 색상
- 흰색에서 연한 노란색
- 수용성
- 물, 메탄올, 에탄올, 디메틸설폭사이드에 용해됩니다. 에테르에 불용성.
- 감도
- Moisture Sensitive
- BRN
- 1532405
- InChIKey
- WOJKKJKETHYEAC-UHFFFAOYSA-N
- CAS 데이터베이스
- 55750-53-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-41-37/38 | ||
| 안전지침서 | 26-36-39 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 10-21 | ||
| HS 번호 | 29251900 |
3-말레이미도-프록실 C화학적 특성, 용도, 생산
화학적 성질
White to yellow solid, powder, crystals or crystaline powder.정의
ChEBI: 6-Maleimidocaproic acid is a medium-chain fatty acid. It contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.주요 응용
6-Maleimidocaproic acid is a sulfhydryl reactive heterobifunctional crosslinking reagent. It can be widely used probe for introducing maleimides groups into biomolecules. A probe for thiol groups in proteins. Spacer Arm: 9.4 Angstroms. Probe for thiol groups (SH-groups) in membrane proteins.Synthesis
Maleic anhydride (29.4 g, 0.3 mol) and 6-aminocaproic acid (39.35 g, 0.3 mol) were refluxed in glacial acetic acid (900 mL) for 16 h. Acetic anhydride (30.6 g, 0.3 mol) was added dropwise over a period of 2 hand reflux was continued for 1 h. The acetic acid was removed under vacuum at 70 °C to yield yellow syrup which solidified. The material was chromatographed over silica using dichloromethane-methanol-acetic acid (100:5:1) affording a crystalline solid (6-Maleimidocaproic acid).
3-말레이미도-프록실 준비 용품 및 원자재
원자재
준비 용품
MC-Val-Cit-PAB
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-
McMMAE
CarbaMic acid, [5-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)pentyl]-, 1,1-diMethylethyl ester
1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2-[(1,1-diMethylethoxy)carbonyl]hydrazide
3-말레이미도-프록실 공급 업체
글로벌( 331)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 |
16728589@qq.com | CHINA | 272 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2968 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |