스트렙톨리신O
|
|
스트렙톨리신O 속성
- 저장 조건
- 2-8°C
- 용해도
- H2O: 용해성1mg/mL
- 물리적 상태
- 동결건조된 분말
- 색상
- 하얀색
안전
유엔번호(UN No.) | UN 2811PIH 6.1 / PGI | ||
---|---|---|---|
WGK 독일 | 3 |
스트렙톨리신O C화학적 특성, 용도, 생산
용도
Permeabilizes membranes to permit cellular uptake of large or charged molecules.일반 설명
Streptolysin O (SLO) is an immunogenic, oxygen-labile toxin, hemolytic exotoxin which is reversibly activated by dithiothreitol. [1] It is released into the extracellular medium along with other toxins, including streptolysin S, during the growth of most strains of group A and many strains of groups C and G Streptococci. [1,2] SLO and Streptolysin S differ from each other in that SLO is immunogenic and oxygen-labile while Streptolysin S is oxygen-stable, nonimmunogenic and only active when associated with a carrier protein.[3] The hemolytic activity of SLO is mediated by formation of multimeric nanopores in cholesterol containing lipid membranes.SLO may be used for cell permeabilization or hemolysis. The susceptibility of hemolysis by SLO varies significantly for erythrocytes from different animal species.[1] Permeabilization of cells using SLO has been performed on multiple cell types and for various applications. For instance it has been used to introduce antisense oligonucleotides into cultured eukaryotic cells;[3] to investigate the effect of guanine nucleotide analogues on phosphatidylinositol metabolism and protein kinase C (PKC) activation in live human T lymphocytes;[4] to monitor cholesterol oxidation within a membrane lipid bilayer; [5] and to label proteins inside living cells using external fluorophores.[6]
Biochem/physiol Actions
This product is produced by recombinant expression in Escherichia coli and contains the complete native protein sequence of SLO (Uniport ID: P0DF96 aa 34-571) without any added purification tags and has calculated molecular weight of 60,144 Dalton. The material is lyophilized from a solution containing 20 mM Sodium Hepes pH 7.5, 150 mM Sodium Chloride and 2 mM EDTA.스트렙톨리신O 준비 용품 및 원자재
원자재
준비 용품
스트렙톨리신O 공급 업체
글로벌( 34)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Nanjing Duly Biotech Co.,Ltd | +undefined18013301590 |
melody@njduly.com | China | 2452 | 58 |
Creative Enzymes | 1-516-855-7709 |
info@creative-enzymes.com | United States | 8748 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23555 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 |
sales01@watsonbiotech.cn | China | 5851 | 58 |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 |
market@aladdin-e.com | China | 25009 | 65 |
Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003 18013301590 |
njduly@126.com | China | 971 | 55 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4428 | 55 |
Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 |
shenlinxing@macklin.cn | China | 16168 | 55 |
스트렙톨리신O 관련 검색:
아세틸아세토산 제2철 실버 아세틸아세토네이트 디스프로슘 트리(2,2,6,6-테트라메틸-3,5-헵탄디오네이트) 알루미늄 아세틸아세토네이트 코발트(II) 아세틸아세토네이트 하이드레이트 아세틸아세톤산 구리
Tosylmethyl isocyanide
Ethyl isocyanoacetate
SALCOMINE
N-BUTYLISOCYANIDE
Tris(2,4-pentanedionato)chroMiuM(III)
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
METHYL ISOCYANOACETATE
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
Benzyl isocyanide
TERT-BUTYL ISOCYANIDE
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
PHENYLSELENOL