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RS 102895

RS 102895 구조식 이미지

카스 번호:: 300815-41-2

상품명:: RS 102895

동의어(영문):: 1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one;RS 102895 HYDROCHLORIDE;CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-;1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride;1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE

CBNumber:: CB6504368

분자식:: C21H21F3N2O2

포뮬러 무게:: 390.4

MOL 파일:: 300815-41-2.mol

속성

안전

용도

공급 업체 95

RS 102895 속성

끓는 점: 446.1±45.0 °C(Predicted)

밀도: 1.33±0.1 g/cm3 (20 ºC 760 Torr)

저장 조건: Desiccate at RT

용해도: DMSO: 18mg/mL, 투명, 무색

물리적 상태: 가루

산도 계수 (pKa): 13.46±0.20(Predicted)

색상: 하얀색

안전

안전지침서	22-24/25
WGK 독일	3

RS 102895 C화학적 특성, 용도, 생산

용도

RS 102895 is a CCR2-selective chemokine receptor inhibitor.

생물학적 활성

CCR2-selective chemokine receptor antagonist (IC 50 values are 0.36 and 17.8 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC 50 values of 32 nM and 1.7 μ M respectively. Also inhibits α 1A , α 1D and 5-HT 1A receptors.

RS 102895 준비 용품 및 원자재

원자재

준비 용품

RS 102895 공급 업체

글로벌( 95)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6710	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9425	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64

RS 102895 관련 검색:

2,3-Dichloro-5-(trifluoromethyl)pyridine 2-fluoro-6-(trifluoroMethyl)benzene-1-sulfonyl chloride Inter-trifluoromethyl iodobenzene 4-(2-AMINOPHENYL)-1-PHENETHYLPIPERIDINE 4-(O-AMINO-PHENYL) PIPERIDINE HYDROCHLORIDE RS 102895 1-Phenethyl-4-phenyl-4-piperidinol SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE