Indacaterol Maleate

Indacaterol Maleate 구조식 이미지
카스 번호:
753498-25-8
상품명:
Indacaterol Maleate
동의어(영문):
Onbrez;Onbrez maleate;Arcapta maleate;Indatarol maleate;ndacaterol Maleate;Indacaterol Maleate;QAB 149 Maleic Acid;IndacaterolMaleate>Indacaterol maleic acid;Indacaterol Maleate(API)
CBNumber:
CB72566367
분자식:
C28H32N2O7
포뮬러 무게:
508.57
MOL 파일:
753498-25-8.mol

Indacaterol Maleate 속성

녹는점
195-197°C (dec.)
저장 조건
Refrigerator
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 옅은 베이지까지
InChIKey
IREJFXIHXRZFER-NVEIECOTNA-N
SMILES
C(/C(=O)O)=C/C(=O)O.[C@H](C1C=CC(O)=C2NC(=O)C=CC=12)(O)CNC1CC2=CC(CC)=C(CC)C=C2C1 |&1:8,r|

안전

HS 번호 29339900

Indacaterol Maleate C화학적 특성, 용도, 생산

화학적 성질

White Solid

용도

A long-acting β2 adrenoreceptor agonist and bronchodilator, for the treatment of asthma and chronic obstructive pulmonary disease.

정의

ChEBI: A maleate salt obtained by reaction of indacaterol with one equivalent of maleic acid. Used for treatment of chronic obstructive pulmonary disease.

상표명

Indacaterol is provided as its maleate salt form. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. 

Clinical Use

Indacaterol is a b-adrenoceptor agonist currently approved in Europe as Onbrez, and is marketed by Novartis. It needs to be taken only once a day, unlike competitors formoterol and salmeterol. These drugs are used in the treatment of chronic obstructive pulmonary disease (COPD) and asthma. Onbrez is administered via an aerosol formulation through a dry powder inhaler. A Phase III trial published in July 2010 suggested that indacaterol is significantly more effective than twice-daily formoterol in improving FEV1 and reduces the need for rescue medication.

부작용

combination of sore throat, runny nose, blocked nose, sneezing; coughing; headache with or without fever; sneezing; muscle pain; muscle spasm; swollen hands, ankles and feet; crushing chest pain (heart problems); neck pain; palpitations (feeling that your heartbeat is unusually fast or irregular); headache; sore throat; cough; runny nose; blocked nose; dry mouth; feeling pressure or pain in the cheeks and forehead (inflammation of the sinuses); chest pain; chest discomfort; pain in muscles, bones or joints; excessive thirst, high urine output, increase appetite with weight loss and tiredness, high level of sugar in the blood (that are signs of a disease called diabetes); tingling and numbness; dizziness vertigo

Indacaterol Maleate 준비 용품 및 원자재

원자재

준비 용품


Indacaterol Maleate 공급 업체

글로벌( 249)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Jewim Pharmaceutical (Shandong) Co., Ltd.
+86-15552509998 +86-15621883869
liutf@jewim.com.cn China 251 58
BIONNA MEDICINE CO.,LTD
01056380788-8515; +8618518759099
790226113@qq.com China 52 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 11013 58
Jinan Million Pharmaceutical Co., Ltd
+86-531-68659554 +8613031714605
info@millionpharm.com China 154 58
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 994 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9348 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3012 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55

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