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napyradiomycin A1

napyradiomycin A1 구조식 이미지

카스 번호:: 103106-24-7

상품명:: napyradiomycin A1

동의어(영문):: WS-9558A;Napyradiomycin A;napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-

CBNumber:: CB81373343

분자식:: C25H30Cl2O5

포뮬러 무게:: 481.41

MOL 파일:: 103106-24-7.mol

속성

안전

용도

공급 업체 9

napyradiomycin A1 속성

끓는 점: 642.5±55.0 °C(Predicted)

밀도: 1.31±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble

물리적 상태: 고체

산도 계수 (pKa): 6.14±0.70(Predicted)

안전

HS 번호	29419000
독성	mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986.

napyradiomycin A1 C화학적 특성, 용도, 생산

개요

Napyradiomycin A₁ is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A₁ is an estrogen receptor antagonist (IC₅₀ = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC₅₀s = 20 and 9.7 μM, respectively).

용도

Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II.

napyradiomycin A1 준비 용품 및 원자재

원자재

준비 용품

napyradiomycin A1 공급 업체

글로벌( 9)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	jiangnan@huidabiotech.com	China	3661	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Zhejiang Huida Biotech Co., LTD	0571-0571-89903882 15990081639	sunshixuan@huidabiotech.com	China	3705	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58

napyradiomycin A1 관련 검색:

5-히드록시-1-테트라론 비스(2-클로로에틸) 에테르 4-Hexanoylresorcinol 2-Methyl-1-tetralone GAMMA-CHLOROBUTYROPHENONE 2',4'-Dichlorovalerophenone 4-CHLORO-4'-HYDROXYBUTYROPHENONE 2-Chloro-2',4'-dihydroxyacetophenone 3-Chloropropiophenone Geranylacetone 2-CHLORO-4'-HYDROXYACETOPHENONE 4-Chlorovalerophenone 3-CHLORO-1-(2-METHYLPHENYL)-1-OXOPROPANE napyradiomycin A1 5-CHLORO-1-(2-METHYLPHENYL)-1-OXOPENTANE 3-CHLORO-2-METHYL-2-BUTANOL 4-CHLORO-1-(2-METHYLPHENYL)-1-OXOBUTANE 5-chloro-1-phenylpentan-1-one