1,2,3,4-TETRAHYDROISOQUINOLINE manufacturers and suppliers

1,2,3,4-TETRAHYDROISOQUINOLINE suppliers

Properties

Melting point:: −30 °C(lit.)

Boiling point:: 232-233 °C(lit.)

Density: 1.064 g/mL at 25 °C(lit.)

vapor pressure: 3.33-97.9Pa at 20-58.5℃

refractive index: n20/D 1.568(lit.)

Flash point:: 210 °F

storage temp.: Keep in dark place,Sealed in dry,Room Temperature

solubility: 20g/l

pka: 9.66±0.20(Predicted)

form: Liquid

color: Clear yellow to brown

Water Solubility: Soluble in water at 20°C 20g/L.

BRN: 116156

InChIKey: UWYZHKAOTLEWKK-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS05,GHS06,GHS08

Signal word: Danger

Hazard statements: H301-H310-H314-H332-H371-H412

Precautionary statements: P260-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36

WGK Germany: 3

RTECS: NX4900000

Hazard Note: Irritant

TSCA: Yes

HS Code: 29334900

Use

1, 2, 3, 4-TETRAHYDROISOQUINOLINE belongs to tetrahydroisoquinoline compound, which is encountered in a number of drugs, tubocurarine, one of the quaternary ammonium muscle relaxants1-3. It is used as a reagent in the preparation of4-(1, 2, 4-oxadiazol-5-yl) piperidine-1-carboxamides as antiproliferative tubulin inhibitors1. It can be used for the synthesis of 1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid (Tic), which has strong applications in peptides and peptidomimetics design and discovery2. 1, 2, 3, 4-tetrahydroisoquinoline has been made into some derivatives with potential for prevention of parkinsonism4, cancer treatment5 and acting as Anticonvulsant Agents6.

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