Finasteride manufacturers and suppliers

Finasteride suppliers

Properties

Melting point:: 253 °C

alpha: 405 -59° (c = 1 in methanol)

Boiling point:: 576.6±50.0 °C(Predicted)

Density: 1.065±0.06 g/cm3(Predicted)

storage temp.: room temp

solubility: DMSO: 32 mg/mL, soluble

pka: 14.17±0.70(Predicted)

form: solid

color: white to beige

Water Solubility: insoluble

Merck: 14,4082

BCS Class: 1

InChIKey: DBEPLOCGEIEOCV-WSBQPABSSA-N

SMILES: [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2

LogP: 3.030

CAS DataBase Reference: 98319-26-7(CAS DataBase Reference)

EPA Substance Registry System: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)- (98319-26-7)

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Danger

Hazard statements: H302-H360FD

Precautionary statements: P202-P264-P270-P280-P301+P312-P308+P313

PPE: dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes: Xn,T,Xi

Risk Statements: 22-61-60-36/37/38

Safety Statements: 36/37/39-45-53-36-26-24/25

WGK Germany: 3

RTECS: CL5245000

HS Code: 29379000

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Acute Tox. 4 Oral
Repr. 1B

Hazardous Substances Data: 98319-26-7(Hazardous Substances Data)

Use

Finasteride, a novel 4-azasteroid, is a breakthrough in the treatment and control of benign prostatic hyperplasia. Mechanistically, it inhibits the prostatic-specific enzyme 5-alpha reductase, thereby decreasing the conversion of testosterone to dihydrotestosterone. It is reportedly effective in reducing urinary symptoms and prostatic volume and increasing maximal urinary flow rate. Finasteride is also being investigated as a treatment for prostatic cancer.

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