Tocainide hydrochloride manufacturers and suppliers

Tocainide hydrochloride suppliers

Tocainide hydrochloride

CAS:: 35891-93-1

MF:: C11H17ClN2O

MW:: 228.71848

Suppliers by country/region

Company Type

Properties

Melting point:: 244-245°C

storage temp.: -20°C Freezer

solubility: Methanol (Slightly), Water (Slightly)

form: Solid

color: Off-White

Safety Information

HS Code: 2924296000

Use

Tocainide hydrochloride,2-amino-2＇ ,6 ＇-propionoxyxylidide hydrochloride (Tonocard)(pKa 7.7), is an analog of lidocaine. It is orally active and haselectrophysiological properties like those of lidocaine. Totalbody clearance of tocainide hydrochloride is only166 mL/min, suggesting that hepatic clearance is not large.Because of low hepatic clearance, the hepatic extraction ratiomust be small; therefore, tocainide hydrochloride is unlikelyto be subject to a substantial first-pass effect. The drug differsfrom lidocaine, in that it lacks two ethyl groups, which providestocainide hydrochloride some protection from first-passhepatic elimination after oral ingestion. Tocainide hydrochlorideis hydrolyzed in a manner similar to that of lidocaine.None of its metabolites is active.

You can find Tocainide hydrochloride suppliers, manufacturers, and distributors from countries such as CHINA, United States and the Canada here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.