PP3 manufacturers and suppliers

PP3 suppliers

Properties

Melting point:: 214-217 °C

Boiling point:: 363.952±35.00 °C(Press: 760.00 Torr)(predicted)

Density: 1.448±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

storage temp.: -20°C

solubility: DMF, DMSO, Hot methanol

pka: 3.89

form: Off-white solid

color: Whit to Off-White

λmax: 240nm(H2O (pH 1))(lit.)

BRN: 198460

CAS DataBase Reference: 5334-30-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319

Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes: Xn,Xi

Risk Statements: 36/37/38-22

Safety Statements: 36/37/39-26

Hazard Note: Irritant

HS Code: 29335995

Use

The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]

You can find PP3 suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.