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ChemicalBook >> CAS DataBase List >> 11-DEOXY PROSTAGLANDIN E1

11-DEOXY PROSTAGLANDIN E1

11-DEOXY PROSTAGLANDIN E1 price.
  • $33 - $443
  • Product name: 11-DEOXY PROSTAGLANDIN E1
  • CAS: 37786-00-8
  • MF: C20H34O4
  • MW: 338.48
  • EINECS:
  • MDL Number:MFCD00065738
  • Synonyms:11-DEOXY PROSTAGLANDIN E1;9-OXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID;7-((1R,2R)-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid;11-deoxy Prostaglandin E1 Exclusive;Prost-13-en-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-
6 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 0.01g
  • ManufacturerAHH
  • Product numberMT-20549
  • Product description9-Oxo-15S-hydroxy-prost-13E-en-1-oicacid 96%
  • Packaging0.01g
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1150AH
  • Product description11-DeoxyprostaglandinE1
  • Packaging5mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13510
  • Product description11-deoxy Prostaglandin E1 ≥96%
  • Packaging500μg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13510
  • Product description11-deoxy Prostaglandin E1 ≥96%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13510
  • Product description11-deoxy Prostaglandin E1 ≥96%
  • Packaging5mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13510
  • Product description11-deoxy Prostaglandin E1 ≥96%
  • Packaging10mg
  • Price$443
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-20549 9-Oxo-15S-hydroxy-prost-13E-en-1-oicacid 96% 0.01g $298 2021-12-16 Buy
AK Scientific 1150AH 11-DeoxyprostaglandinE1 5mg $380 2021-12-16 Buy
Cayman Chemical 13510 11-deoxy Prostaglandin E1 ≥96% 500μg $33 2024-03-01 Buy
Cayman Chemical 13510 11-deoxy Prostaglandin E1 ≥96% 1mg $62 2024-03-01 Buy
Cayman Chemical 13510 11-deoxy Prostaglandin E1 ≥96% 5mg $254 2024-03-01 Buy
Cayman Chemical 13510 11-deoxy Prostaglandin E1 ≥96% 10mg $443 2024-03-01 Buy

Properties

Boiling point :509.7±35.0 °C(Predicted)
Density :1.070±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form :A crystalline solid
pka :4.77±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2. However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC50 of 0.25 μM. 11-deoxy PGE1 also exhibits vasodepressor and bronchodilator responses in guinea pigs. 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The Ki values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.

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