N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
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- $62 - $815
- Product name: N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
- CAS: 269390-69-4
- MF: C19H16ClN3O
- MW: 337.8
- EINECS:
- MDL Number:MFCD09037563
- Synonyms:VEGFR Tyrosine Kinase Inhibitor II;N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE;VEGF RECEPTOR TYROSINE KINASE INHIBITOR II;Valatinib;Benzamide, N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-;VEGFR-IN-1;VEGFR Tyrosine Kinase;VEGFR IN 1,VEGFRIN1
9 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2.5mg
- 5MG
- 10mg
- ManufacturerAK Scientific
- Product number3074CR
- Product descriptionN-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
- Packaging1mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0352681
- Product descriptionN-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 95.00%
- Packaging5MG
- Price$495.87
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4603
- Product descriptionVEGFRTyrosineKinaseInhibitorII
- Packaging1mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4603
- Product descriptionVEGFRTyrosineKinaseInhibitorII
- Packaging5mg
- Price$204
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17654
- Product descriptionVEGFR Tyrosine Kinase Inhibitor II ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17654
- Product descriptionVEGFR Tyrosine Kinase Inhibitor II ≥98%
- Packaging5mg
- Price$180
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number676481
- Product descriptionVEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem
- Packaging5MG
- Price$253
- Updated2026-03-19
- Buy
- ManufacturerTRC
- Product numberV756803
- Product descriptionVEGFRTyrosineKinaseInhibitorII
- Packaging2.5mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberV756803
- Product descriptionVEGFRTyrosineKinaseInhibitorII
- Packaging10mg
- Price$815
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3074CR | N-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide | 1mg | $166 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0352681 | N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 95.00% | 5MG | $495.87 | 2021-12-16 | Buy |
| ApexBio Technology | C4603 | VEGFRTyrosineKinaseInhibitorII | 1mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | C4603 | VEGFRTyrosineKinaseInhibitorII | 5mg | $204 | 2021-12-16 | Buy |
| Cayman Chemical | 17654 | VEGFR Tyrosine Kinase Inhibitor II ≥98% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 17654 | VEGFR Tyrosine Kinase Inhibitor II ≥98% | 5mg | $180 | 2024-03-01 | Buy |
| Sigma-Aldrich | 676481 | VEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem | 5MG | $253 | 2026-03-19 | Buy |
| TRC | V756803 | VEGFRTyrosineKinaseInhibitorII | 2.5mg | $270 | 2021-12-16 | Buy |
| TRC | V756803 | VEGFRTyrosineKinaseInhibitorII | 10mg | $815 | 2021-12-16 | Buy |
Properties
Boiling point :463.6±40.0 °C(Predicted)
Density :1.331±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml
form :A crystalline solid
pka :12.62±0.70(Predicted)
color :White to off-white
InChI :1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)
InChIKey :GGPZCOONYBPZEW-UHFFFAOYSA-N
SMILES :Clc1ccc(cc1)NC(=O)c2c(cccc2)NCc3ccncc3
Density :1.331±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml
form :A crystalline solid
pka :12.62±0.70(Predicted)
color :White to off-white
InChI :1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)
InChIKey :GGPZCOONYBPZEW-UHFFFAOYSA-N
SMILES :Clc1ccc(cc1)NC(=O)c2c(cccc2)NCc3ccncc3
Safety Information
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Description
VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively). It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 μM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 μM). VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.More related product prices
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