[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547)
![[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547) price.](/CAS/GIF/741713-40-6.gif)
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- $120 - $3200
- Product name: [4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547)
- CAS: 741713-40-6
- MF: C18H21F2N5O4S
- MW: 441.45
- EINECS:
- MDL Number:MFCD09970629
- Synonyms:[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547);R547;[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone;Ro 4584820;[4-aMino-2-[[1-(Methylsulfonyl)-4-piperidinyl]aMino]-5-pyriMidinyl](2;3-difluoro-6-Methoxyphenyl)-;R547(Ro 4584820);5-[(2,3-difluoro-6-Methoxyphenyl)carbonyl]-2-N-(1-Methanesulfonylpiperidin-4-yl)pyriMidine-2,4-diaMine
17 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 2x25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberY0369
- Product descriptionR547
- Packaging1mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0369
- Product descriptionR547
- Packaging5mg
- Price$695
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0030159
- Product description[4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00%
- Packaging1MG
- Price$225.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0030159
- Product description[4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00%
- Packaging5MG
- Price$499.85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8642
- Product descriptionR547
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8642
- Product descriptionR547
- Packaging100mg
- Price$1001
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1983
- Product descriptionR547 99%
- Packaging2x25mg
- Price$484
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17905
- Product descriptionR547 ≥98%
- Packaging1mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17905
- Product descriptionR547 ≥98%
- Packaging5mg
- Price$537
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM167858
- Product description(4-Amino-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone 98%
- Packaging100mg
- Price$1421
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0022
- Product descriptionR547 99.66%
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0022
- Product descriptionR547 99.66%
- Packaging50mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000911
- Product descriptionR547 98+%
- Packaging25mg
- Price$608
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000911
- Product descriptionR547 98+%
- Packaging100mg
- Price$1520
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC2068
- Product descriptionR547 >98%
- Packaging250mg
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC2068
- Product descriptionR547 >98%
- Packaging1g
- Price$3200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0369 | R547 | 1mg | $232 | 2021-12-16 | Buy |
| AK Scientific | Y0369 | R547 | 5mg | $695 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0030159 | [4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00% | 1MG | $225.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0030159 | [4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00% | 5MG | $499.85 | 2021-12-16 | Buy |
| ApexBio Technology | A8642 | R547 | 10mg | $270 | 2021-12-16 | Buy |
| ApexBio Technology | A8642 | R547 | 100mg | $1001 | 2021-12-16 | Buy |
| Axon Medchem | Axon1983 | R547 99% | 2x25mg | $484 | 2021-12-16 | Buy |
| Cayman Chemical | 17905 | R547 ≥98% | 1mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 17905 | R547 ≥98% | 5mg | $537 | 2024-03-01 | Buy |
| Chemenu | CM167858 | (4-Amino-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone 98% | 100mg | $1421 | 2021-12-16 | Buy |
| ChemScene | CS-0022 | R547 99.66% | 10mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-0022 | R547 99.66% | 50mg | $700 | 2021-12-16 | Buy |
| Crysdot | CD31000911 | R547 98+% | 25mg | $608 | 2021-12-16 | Buy |
| Crysdot | CD31000911 | R547 98+% | 100mg | $1520 | 2021-12-16 | Buy |
| DC Chemicals | DC2068 | R547 >98% | 250mg | $1900 | 2021-12-16 | Buy |
| DC Chemicals | DC2068 | R547 >98% | 1g | $3200 | 2021-12-16 | Buy |
Properties
Boiling point :703.7±70.0 °C(Predicted)
Density :1.49
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :4.22±0.10(Predicted)
Density :1.49
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :4.22±0.10(Predicted)
Safety Information
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Description
R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.More related product prices
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![[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547)](https://img.chemicalbook.com/ProductImageEN/2019-12/small/44a7c753-e8a5-4221-b6f9-c8817bba8af5.jpg){kind=small}