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ChemicalBook >> CAS DataBase List >> 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione

5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione

5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione price.
  • $44 - $2200
  • Product name: 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione
  • CAS: 958852-01-2
  • MF: C18H11N3O2S
  • MW: 333.36
  • EINECS:
  • MDL Number:MFCD18074517
  • Synonyms:5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione;GSK 1059615;GSK 1059615 SodiuM Salt Hydrate;SK1059615;(5Z)-5-[[4-(4-pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione sodium salt hydrate;GSK-615;GSK1059615;GSK 1059615; GSK-1059615;GSK 1059615;GSK-1059615
Price53 Properties Safety Information Description
53 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
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  • Manufactureraablocks
  • Product numberAA005WVA
  • Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
  • Packaging1mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005WVA
  • Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
  • Packaging5mg
  • Price$69
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005WVA
  • Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
  • Packaging10mg
  • Price$98
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005WVA
  • Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
  • Packaging25mg
  • Price$179
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005WVA
  • Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
  • Packaging50mg
  • Price$283
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005WVA
  • Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
  • Packaging100mg
  • Price$417
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50916
  • Product descriptionGSK1059615 98%
  • Packaging25MG
  • Price$395
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50916
  • Product descriptionGSK1059615 98%
  • Packaging5MG
  • Price$130
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50916
  • Product descriptionGSK1059615 98%
  • Packaging2MG
  • Price$65
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50916
  • Product descriptionGSK1059615 98%
  • Packaging100MG
  • Price$1150
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000877
  • Product descriptionGSK-1059615 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000877
  • Product descriptionGSK-1059615 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2176
  • Product descriptionGSK1059615
  • Packaging50mg
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2176
  • Product descriptionGSK1059615
  • Packaging10mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2176
  • Product descriptionGSK1059615
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2176
  • Product descriptionGSK1059615
  • Packaging5mg
  • Price$74
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005WVA (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione 1mg $44 2026-05-28 Buy
aablocks AA005WVA (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione 5mg $69 2026-05-28 Buy
aablocks AA005WVA (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione 10mg $98 2026-05-28 Buy
aablocks AA005WVA (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione 25mg $179 2026-05-28 Buy
aablocks AA005WVA (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione 50mg $283 2026-05-28 Buy
aablocks AA005WVA (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione 100mg $417 2026-05-28 Buy
ACHEMBLOCK P50916 GSK1059615 98% 25MG $395 2026-05-27 Buy
ACHEMBLOCK P50916 GSK1059615 98% 5MG $130 2026-05-27 Buy
ACHEMBLOCK P50916 GSK1059615 98% 2MG $65 2026-05-27 Buy
ACHEMBLOCK P50916 GSK1059615 98% 100MG $1150 2026-05-27 Buy
American Custom Chemicals Corporation KIN0000877 GSK-1059615 95.00% 100MG $1871.1 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000877 GSK-1059615 95.00% 10MG $739.2 2021-12-16 Buy
ApexBio Technology B2176 GSK1059615 50mg $495 2021-12-16 Buy
ApexBio Technology B2176 GSK1059615 10mg $115 2021-12-16 Buy
ApexBio Technology B2176 GSK1059615 5mg $80 2021-12-16 Buy
ApexBio Technology B2176 GSK1059615 5mg $74 2026-05-06 Buy
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Properties

Melting point :>290°C (dec.)
storage temp. :Store at +4°C
solubility :H2O: ≥8mg/mL
form :powder
color :yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PI 3-kinase α (PI3Kα) is a critical regulator of cell growth and transformation. Its signaling pathway is the most commonly mutated pathway in human cancers. GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM) and the common activating mutants of p110α (E542K, E545K, and H1047R) found in cancer. It prevents proliferation in BT474 tumor xenografts and reduces MAPK signaling following twice daily dosing at 25 mg/kg.

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Suppliers and manufacturers

career henan chemical co
5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione
$950.00 /2KG
5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione CAS:958852-01-2
TargetMol Chemicals Inc.
GSK1059615
$61.00 /5mg
GSK1059615 CAS:958852-01-2
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
CONIER CHEM AND PHARMA LIMITED
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
changzhou huayang technology co., ltd
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.