A66
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- $32 - $4171.86
- Product name: A66
- CAS: 1166227-08-2
- MF: C17H23N5O2S2
- MW: 393.53
- EINECS:-0
- MDL Number:MFCD22378485
- Synonyms:(2S)-N1-[2-(tert-Butyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide;(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide;(2S)-N1-[2-(tert-Butyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide A 66;CS-435;A66, 98%, a potent and specific p110α inhibitor;(2S)-N1-[2-(1,1-Dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide;A 66;A-66;1,2-Pyrrolidinedicarboxamide, N1-[2-(1,1-dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-, (2S)-
77 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Synthonix
- TRC
Package
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5 mg
- 25 mg
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66
- Packaging2mg
- Price$44
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66
- Packaging5mg
- Price$57
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66 ≥98%
- Packaging1mg
- Price$32
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66
- Packaging10mg
- Price$81
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66 98%
- Packaging25mg
- Price$102
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66 98%
- Packaging50mg
- Price$172
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66
- Packaging100mg
- Price$327
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000CT6
- Product descriptionA66
- Packaging200mg
- Price$451
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50940
- Product descriptionA66 98%
- Packaging100MG
- Price$460
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50940
- Product descriptionA66 98%
- Packaging100MG
- Price$460
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50940
- Product descriptionA66 98%
- Packaging25MG
- Price$175
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50940
- Product descriptionA66 98%
- Packaging25MG
- Price$175
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX7447
- Product description(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7447
- Product description(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102947
- Product descriptionA66 98+%
- Packaging50mg
- Price$622
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102947
- Product descriptionA66 98+%
- Packaging10mg
- Price$203
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000CT6 | A66 | 2mg | $44 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 | 5mg | $57 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 ≥98% | 1mg | $32 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 | 10mg | $81 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 98% | 25mg | $102 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 98% | 50mg | $172 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 | 100mg | $327 | 2026-05-25 | Buy |
| aablocks | AA000CT6 | A66 | 200mg | $451 | 2026-05-25 | Buy |
| ACHEMBLOCK | P50940 | A66 98% | 100MG | $460 | 2026-05-25 | Buy |
| ACHEMBLOCK | P50940 | A66 98% | 100MG | $460 | 2026-05-27 | Buy |
| ACHEMBLOCK | P50940 | A66 98% | 25MG | $175 | 2026-05-25 | Buy |
| ACHEMBLOCK | P50940 | A66 98% | 25MG | $175 | 2026-05-27 | Buy |
| AK Scientific | X7447 | (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide | 10mg | $218 | 2021-12-16 | Buy |
| AK Scientific | X7447 | (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide | 50mg | $640 | 2021-12-16 | Buy |
| Ambeed | A102947 | A66 98+% | 50mg | $622 | 2021-12-16 | Buy |
| Ambeed | A102947 | A66 98+% | 10mg | $203 | 2021-12-16 | Buy |
Properties
Density :1.354
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥19.7 mg/mL in DMSO; ≥2.63 mg/mL in EtOH with gentle warming
form :solid
pka :6.27±0.70(Predicted)
color :Off-white to light yellow
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥19.7 mg/mL in DMSO; ≥2.63 mg/mL in EtOH with gentle warming
form :solid
pka :6.27±0.70(Predicted)
color :Off-white to light yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
A-66 is a potent, selective inhibitor of the PI3K isoform p110α (IC50 = 32 nM in a cell-free assay). It displays over 100-fold selectivity for p110α over other isoforms. A-66 is effective in vivo, suppressing the growth of SK-OV-3 tumor xenografts in mice. It also impairs all measures of in vivo insulin action in mice. A-66 partially suppresses B cell receptor-dependent Akt activation and proliferation.More related product prices
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