ACPT-I
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- $44 - $1456
- Product name: ACPT-I
- CAS: 194918-76-8
- MF: C8H11NO6
- MW: 217.18
- EINECS:
- MDL Number:MFCD06795869
- Synonyms:ACPT-I;4-AMINO-1BETA,2BETA,4BETA-CYCLOPENTANETRICARBOXYLIC ACID;(1S,3R,4S)-1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACID;1,2,4-Cyclopentanetricarboxylic acid, 4-amino-, (1α,2α,4β)-;ACPT I,ACPTI
11 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Tocris
- TRC
Package
- 1mg
- 10
- 5mg
- 50
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number0044CQ
- Product descriptionAcpt-I
- Packaging10mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0073436
- Product description1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACID 95.00%
- Packaging10MG
- Price$721.59
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5051
- Product descriptionACPT-I
- Packaging10mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5051
- Product descriptionACPT-I
- Packaging50mg
- Price$1456
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number78010
- Product descriptionACPT-I ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number78010
- Product descriptionACPT-I ≥98%
- Packaging5mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number78010
- Product descriptionACPT-I ≥98%
- Packaging10mg
- Price$235
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number78010
- Product descriptionACPT-I ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1111
- Product descriptionACPT-I
- Packaging10
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1111
- Product descriptionACPT-I
- Packaging50
- Price$962
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA115665
- Product descriptionACPT-I
- Packaging1mg
- Price$115
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0044CQ | Acpt-I | 10mg | $360 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0073436 | 1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACID 95.00% | 10MG | $721.59 | 2021-12-16 | Buy |
| ApexBio Technology | B5051 | ACPT-I | 10mg | $345 | 2021-12-16 | Buy |
| ApexBio Technology | B5051 | ACPT-I | 50mg | $1456 | 2021-12-16 | Buy |
| Cayman Chemical | 78010 | ACPT-I ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 78010 | ACPT-I ≥98% | 5mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 78010 | ACPT-I ≥98% | 10mg | $235 | 2024-03-01 | Buy |
| Cayman Chemical | 78010 | ACPT-I ≥98% | 25mg | $533 | 2024-03-01 | Buy |
| Tocris | 1111 | ACPT-I | 10 | $228 | 2021-12-16 | Buy |
| Tocris | 1111 | ACPT-I | 50 | $962 | 2021-12-16 | Buy |
| TRC | A115665 | ACPT-I | 1mg | $115 | 2021-12-16 | Buy |
Properties
Boiling point :440.4±45.0 °C(Predicted)
Density :1.651±0.06 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :Soluble to 10 mM in water and to 50 mM in 1.1eq. NaOH
form :Powder
pka :1.85±0.60(Predicted)
color :White to off-white
Density :1.651±0.06 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :Soluble to 10 mM in water and to 50 mM in 1.1eq. NaOH
form :Powder
pka :1.85±0.60(Predicted)
color :White to off-white
Safety Information
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Description
ACPT-I is an agonist of the group III metabotropic glutamate receptors (mGluRs) mGluR4a and mGluR8 (EC50s = 7.2 and 8.2 μM, respectively) that has no effect on mGluR1a or mGluR2. It has diverse biological activity, including neuroprotective, anticonvulsant, and anxiolytic-like effects. ACPT-I (1-200 μM) reduces cell death following oxygen-glucose deprivation in primary neuronal cultures and in a rat model of middle cerebral artery occlusion when used at a dose of 30 mg/kg. It is neuroprotective against excitotoxicity induced by kainite in vitro and in vivo and reduces the incidence of clonic seizures in various seizure models in mice and rats (ED50s = 0.08-49.3 nM, i.c.v.). ACPT-I also has anxiolytic-like effects in mice and rats, however, these effects can be blocked by WAY-100635 and flumazenil , indicating the involvement of the serotonin (5-HT) receptor subtype 5-HT1A and GABAA receptor.Related product price
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