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ChemicalBook >> CAS DataBase List >> AMG-706

AMG-706

$21 - $1805
Product name: AMG-706
CAS: 857876-30-3
MF: C22H29N5O9P2
MW: 569.441282
EINECS:
MDL Number:MFCD12407403
Synonyms:Motesanib, Diphosphate Salt;AMG-706;Motesanib(AMG-706);Motesanib diphosphate;Motesanib diphosphate [usan];Unii-T6Q3060U91;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate;N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate

Price77 Properties Safety Information Description

77 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
American Custom Chemicals Corporation
ApexBio Technology
Apolloscientific
AvaChem
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
Usbiological

Package

0.05g
0.1g
200mg
0.25g
500mg
0.5g
10 mg
10mM*1mLinDMSO
1000mg
10mM(in1mLDMSO)
1mg
5mg
10mg
50mg
100mg
25MG
250MG
1G
10mM(in 1mL DMSO)

Manufactureraablocks
Product numberAA00G2I5
Product descriptionMotesanib Diphosphate 97%
Packaging1mg
Price$21
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G2I5
Product descriptionMotesanib Diphosphate 97%
Packaging5mg
Price$26
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G2I5
Product descriptionMotesanib Diphosphate 97%
Packaging10mg
Price$38
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G2I5
Product descriptionMotesanib Diphosphate 97
Packaging50mg
Price$157
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G2I5
Product descriptionMotesanib Diphosphate 97
Packaging100mg
Price$258
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberQ70236
Product descriptionMotesanib Diphosphate 98%
Packaging250MG
Price$420
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ70236
Product descriptionMotesanib Diphosphate 98%
Packaging1G
Price$835
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ70236
Product descriptionMotesanib Diphosphate 98%
Packaging100MG
Price$250
Updated2026-05-27
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0006359
Product descriptionMOTESANIB DIPHOSPHATE 95.00%
Packaging5MG
Price$268.4
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0006359
Product descriptionMOTESANIB DIPHOSPHATE 95.00%
Packaging10MG
Price$702.66
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0006359
Product descriptionMOTESANIB DIPHOSPHATE 95.00%
Packaging25MG
Price$798.7
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA5017
Product descriptionMotesanibDiphosphate(AMG-706)
Packaging50mg
Price$155
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA5017
Product descriptionMotesanib Diphosphate (AMG-706)
Packaging100mg
Price$231
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA5017
Product descriptionMotesanib Diphosphate (AMG-706)
Packaging25mg
Price$88
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA5017
Product descriptionMotesanibDiphosphate(AMG-706)
Packaging10mM(in 1mL DMSO)
Price$55
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA5017
Product descriptionMotesanib Diphosphate (AMG-706)
Packaging10mg
Price$55
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00G2I5	Motesanib Diphosphate 97%	1mg	$21	2026-05-28	Buy
aablocks	AA00G2I5	Motesanib Diphosphate 97%	5mg	$26	2026-05-28	Buy
aablocks	AA00G2I5	Motesanib Diphosphate 97%	10mg	$38	2026-05-28	Buy
aablocks	AA00G2I5	Motesanib Diphosphate 97	50mg	$157	2026-05-28	Buy
aablocks	AA00G2I5	Motesanib Diphosphate 97	100mg	$258	2026-05-28	Buy
ACHEMBLOCK	Q70236	Motesanib Diphosphate 98%	250MG	$420	2026-05-27	Buy
ACHEMBLOCK	Q70236	Motesanib Diphosphate 98%	1G	$835	2026-05-27	Buy
ACHEMBLOCK	Q70236	Motesanib Diphosphate 98%	100MG	$250	2026-05-27	Buy
American Custom Chemicals Corporation	API0006359	MOTESANIB DIPHOSPHATE 95.00%	5MG	$268.4	2021-12-16	Buy
American Custom Chemicals Corporation	API0006359	MOTESANIB DIPHOSPHATE 95.00%	10MG	$702.66	2021-12-16	Buy
American Custom Chemicals Corporation	API0006359	MOTESANIB DIPHOSPHATE 95.00%	25MG	$798.7	2021-12-16	Buy
ApexBio Technology	A5017	MotesanibDiphosphate(AMG-706)	50mg	$155	2021-12-16	Buy
ApexBio Technology	A5017	Motesanib Diphosphate (AMG-706)	100mg	$231	2026-05-06	Buy
ApexBio Technology	A5017	Motesanib Diphosphate (AMG-706)	25mg	$88	2026-05-06	Buy
ApexBio Technology	A5017	MotesanibDiphosphate(AMG-706)	10mM(in 1mL DMSO)	$55	2021-12-16	Buy
ApexBio Technology	A5017	Motesanib Diphosphate (AMG-706)	10mg	$55	2026-05-06	Buy

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Properties

storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥28.45 mg/mL in DMSO; insoluble in H2O; ≥3.47 mg/mL in EtOH with ultrasonic
form :Powder
color :White to off-white
InChIKey :ONDPWWDPQDCQNJ-UHFFFAOYSA-N
SMILES :CC1(C2C=CC(=CC=2NC1)NC(=O)C1C=CC=NC=1NCC1C=CN=CC=1)C.OP(=O)(O)O.OP(=O)(O)O

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AMG 706 is a multikinase inhibitor that predominantly targets receptor tyrosine kinases, including VEGFR1, VEGFR2, VEGFR3, c-Kit, PDGFR, and RET (IC50s = 2, 3, 6, 8, 84, and 59 nM, respectively). It also potently inhibits CSF1R and ZAK (IC50s = 5.6 and 8 nM, respectively), as well as several mutants of c-Kit. AMG 706 inhibits the proliferation of human endothelial cells induced by VEGF but not FGF. Oral administration of AMG 706 blocks VEGF-induced angiogenesis in the rat corneal model and induces regression of established A431 xenografts in mice.

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Suppliers and manufacturers

career henan chemical co

$2.00
AMG-706 CAS:857876-30-3

TargetMol Chemicals Inc.

$36.00
Motesanib Diphosphate CAS:857876-30-3

ATK CHEMICAL COMPANY LIMITED

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Dideu Industries Group Limited

BOC Sciences

Dayang Chem (Hangzhou) Co.,Ltd.

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

PT CHEM GROUP LIMITED

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AMG-706

Properties

Safety Information

Description

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