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ChemicalBook >> CAS DataBase List >> AMG-706

AMG-706

AMG-706 price.
  • $21 - $1805
  • Product name: AMG-706
  • CAS: 857876-30-3
  • MF: C22H29N5O9P2
  • MW: 569.441282
  • EINECS:
  • MDL Number:MFCD12407403
  • Synonyms:Motesanib, Diphosphate Salt;AMG-706;Motesanib(AMG-706);Motesanib diphosphate;Motesanib diphosphate [usan];Unii-T6Q3060U91;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate;N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate
Price55 Properties Safety Information Description
55 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Usbiological
Package
  • 0.05g
  • 0.1g
  • 200mg
  • 0.25g
  • 500mg
  • 0.5g
  • 10 mg
  • 10mM*1mLinDMSO
  • 1000mg
  • 10mM(in1mLDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 25MG
  • 250MG
  • 1G
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00G2I5
  • Product descriptionMotesanib Diphosphate 97%
  • Packaging1mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G2I5
  • Product descriptionMotesanib Diphosphate 97%
  • Packaging5mg
  • Price$26
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G2I5
  • Product descriptionMotesanib Diphosphate 97%
  • Packaging10mg
  • Price$38
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G2I5
  • Product descriptionMotesanib Diphosphate 97
  • Packaging50mg
  • Price$157
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G2I5
  • Product descriptionMotesanib Diphosphate 97
  • Packaging100mg
  • Price$258
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70236
  • Product descriptionMotesanib Diphosphate 98%
  • Packaging100MG
  • Price$250
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70236
  • Product descriptionMotesanib Diphosphate 98%
  • Packaging250MG
  • Price$420
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70236
  • Product descriptionMotesanib Diphosphate 98%
  • Packaging1G
  • Price$835
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006359
  • Product descriptionMOTESANIB DIPHOSPHATE 95.00%
  • Packaging10MG
  • Price$702.66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006359
  • Product descriptionMOTESANIB DIPHOSPHATE 95.00%
  • Packaging25MG
  • Price$798.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006359
  • Product descriptionMOTESANIB DIPHOSPHATE 95.00%
  • Packaging5MG
  • Price$268.4
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanib Diphosphate (AMG-706)
  • Packaging100mg
  • Price$231
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanib Diphosphate (AMG-706)
  • Packaging25mg
  • Price$88
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanib Diphosphate (AMG-706)
  • Packaging50mg
  • Price$121
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanibDiphosphate(AMG-706)
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanib Diphosphate (AMG-706)
  • Packaging10mg
  • Price$55
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00G2I5 Motesanib Diphosphate 97% 1mg $21 2026-05-28 Buy
aablocks AA00G2I5 Motesanib Diphosphate 97% 5mg $26 2026-05-28 Buy
aablocks AA00G2I5 Motesanib Diphosphate 97% 10mg $38 2026-05-28 Buy
aablocks AA00G2I5 Motesanib Diphosphate 97 50mg $157 2026-05-28 Buy
aablocks AA00G2I5 Motesanib Diphosphate 97 100mg $258 2026-05-28 Buy
ACHEMBLOCK Q70236 Motesanib Diphosphate 98% 100MG $250 2026-05-27 Buy
ACHEMBLOCK Q70236 Motesanib Diphosphate 98% 250MG $420 2026-05-27 Buy
ACHEMBLOCK Q70236 Motesanib Diphosphate 98% 1G $835 2026-05-27 Buy
American Custom Chemicals Corporation API0006359 MOTESANIB DIPHOSPHATE 95.00% 10MG $702.66 2021-12-16 Buy
American Custom Chemicals Corporation API0006359 MOTESANIB DIPHOSPHATE 95.00% 25MG $798.7 2021-12-16 Buy
American Custom Chemicals Corporation API0006359 MOTESANIB DIPHOSPHATE 95.00% 5MG $268.4 2021-12-16 Buy
ApexBio Technology A5017 Motesanib Diphosphate (AMG-706) 100mg $231 2026-05-06 Buy
ApexBio Technology A5017 Motesanib Diphosphate (AMG-706) 25mg $88 2026-05-06 Buy
ApexBio Technology A5017 Motesanib Diphosphate (AMG-706) 50mg $121 2026-05-06 Buy
ApexBio Technology A5017 MotesanibDiphosphate(AMG-706) 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A5017 Motesanib Diphosphate (AMG-706) 10mg $55 2026-05-06 Buy
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Properties

storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥28.45 mg/mL in DMSO; insoluble in H2O; ≥3.47 mg/mL in EtOH with ultrasonic
form :Powder
color :White to off-white
InChIKey :ONDPWWDPQDCQNJ-UHFFFAOYSA-N
SMILES :CC1(C2C=CC(=CC=2NC1)NC(=O)C1C=CC=NC=1NCC1C=CN=CC=1)C.OP(=O)(O)O.OP(=O)(O)O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AMG 706 is a multikinase inhibitor that predominantly targets receptor tyrosine kinases, including VEGFR1, VEGFR2, VEGFR3, c-Kit, PDGFR, and RET (IC50s = 2, 3, 6, 8, 84, and 59 nM, respectively). It also potently inhibits CSF1R and ZAK (IC50s = 5.6 and 8 nM, respectively), as well as several mutants of c-Kit. AMG 706 inhibits the proliferation of human endothelial cells induced by VEGF but not FGF. Oral administration of AMG 706 blocks VEGF-induced angiogenesis in the rat corneal model and induces regression of established A431 xenografts in mice.

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Suppliers and manufacturers

Tianjin Kailiqi Biotechnology Co., Ltd. Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Chemsky (shanghai) International Co.,Ltd Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. NCE Biomedical Co.,Ltd. Haoyuan Chemexpress Co., Ltd. Shanghai Aladdin Bio-Chem Technology Co.,LTD Guangzhou Isun Pharmaceutical Co., Ltd