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ChemicalBook >> CAS DataBase List >> AMG-706

AMG-706

AMG-706 price.
  • $35 - $1805
  • Product name: AMG-706
  • CAS: 857876-30-3
  • MF: C22H29N5O9P2
  • MW: 569.441282
  • EINECS:
  • MDL Number:MFCD12407403
  • Synonyms:Motesanib, Diphosphate Salt;AMG-706;Motesanib(AMG-706);Motesanib diphosphate;Motesanib diphosphate [usan];Unii-T6Q3060U91;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate;N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate
Price31 Properties Safety Information Description
31 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Usbiological
Package
  • 1mg
  • 5MG
  • 10MG
  • 25MG
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 1000mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006359
  • Product descriptionMOTESANIB DIPHOSPHATE 95.00%
  • Packaging5MG
  • Price$268.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006359
  • Product descriptionMOTESANIB DIPHOSPHATE 95.00%
  • Packaging10MG
  • Price$702.66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006359
  • Product descriptionMOTESANIB DIPHOSPHATE 95.00%
  • Packaging25MG
  • Price$798.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanibDiphosphate(AMG-706)
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5017
  • Product descriptionMotesanibDiphosphate(AMG-706)
  • Packaging50mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0030
  • Product descriptionMotesanibDiphosphateSalt
  • Packaging10mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0030
  • Product descriptionMotesanibDiphosphateSalt
  • Packaging50mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0030
  • Product descriptionMotesanibDiphosphateSalt
  • Packaging100mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2554
  • Product descriptionMotesanib Diphosphate
  • Packaging10mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2554
  • Product descriptionMotesanib Diphosphate
  • Packaging100mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2554
  • Product descriptionMotesanib Diphosphate
  • Packaging1g
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181060
  • Product descriptionMotesanib Diphosphate (AMG-706) >98%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181060
  • Product descriptionMotesanib Diphosphate (AMG-706) >98%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181060
  • Product descriptionMotesanib Diphosphate (AMG-706) >98%
  • Packaging1000mg
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26093
  • Product descriptionMotesanib diphosphate
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26093
  • Product descriptionMotesanib diphosphate
  • Packaging50mg
  • Price$262.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0006359 MOTESANIB DIPHOSPHATE 95.00% 5MG $268.4 2021-12-16 Buy
American Custom Chemicals Corporation API0006359 MOTESANIB DIPHOSPHATE 95.00% 10MG $702.66 2021-12-16 Buy
American Custom Chemicals Corporation API0006359 MOTESANIB DIPHOSPHATE 95.00% 25MG $798.7 2021-12-16 Buy
ApexBio Technology A5017 MotesanibDiphosphate(AMG-706) 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A5017 MotesanibDiphosphate(AMG-706) 50mg $155 2021-12-16 Buy
Apolloscientific BIFK0030 MotesanibDiphosphateSalt 10mg $66 2021-12-16 Buy
Apolloscientific BIFK0030 MotesanibDiphosphateSalt 50mg $218 2021-12-16 Buy
Apolloscientific BIFK0030 MotesanibDiphosphateSalt 100mg $348 2021-12-16 Buy
AvaChem 2554 Motesanib Diphosphate 10mg $35 2021-12-16 Buy
AvaChem 2554 Motesanib Diphosphate 100mg $185 2021-12-16 Buy
AvaChem 2554 Motesanib Diphosphate 1g $1350 2021-12-16 Buy
Biorbyt Ltd orb181060 Motesanib Diphosphate (AMG-706) >98% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb181060 Motesanib Diphosphate (AMG-706) >98% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb181060 Motesanib Diphosphate (AMG-706) >98% 1000mg $1802 2021-12-16 Buy
Biosynth Carbosynth FM26093 Motesanib diphosphate 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FM26093 Motesanib diphosphate 50mg $262.5 2021-12-16 Buy
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Properties

storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥28.45 mg/mL in DMSO; insoluble in H2O; ≥3.47 mg/mL in EtOH with ultrasonic
form :Powder

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AMG 706 is a multikinase inhibitor that predominantly targets receptor tyrosine kinases, including VEGFR1, VEGFR2, VEGFR3, c-Kit, PDGFR, and RET (IC50s = 2, 3, 6, 8, 84, and 59 nM, respectively). It also potently inhibits CSF1R and ZAK (IC50s = 5.6 and 8 nM, respectively), as well as several mutants of c-Kit. AMG 706 inhibits the proliferation of human endothelial cells induced by VEGF but not FGF. Oral administration of AMG 706 blocks VEGF-induced angiogenesis in the rat corneal model and induces regression of established A431 xenografts in mice.

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Suppliers and manufacturers

career henan chemical co
AMG-706
$2.00 /1kg
AMG-706 CAS:857876-30-3
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited