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ChemicalBook >> CAS DataBase List >> APD668

APD668

APD668 price.
  • $44 - $1365
  • Product name: APD668
  • CAS: 832714-46-2
  • MF: C21H24FN5O5S
  • MW: 477.51
  • EINECS:
  • MDL Number:MFCD12032117
  • Synonyms:APD668;APD668 ISOPROPYL 4-(1-(2-FLUORO-4-(METHYLSULFONYL)PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLOXY)PIPERIDINE-1-CARBOXYLATE;isopropyl 4-((1-(2-fluoro-4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)oxy)piperidine-1-carboxylate APD668;APD 668, >=98%;4-[[1-(2-Fluoro-4-methylsulfonylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy]piperidine-1-carboxylic acid isopropyl ester;1-Piperidinecarboxylic acid,4-[[1-[2-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy]-, 1-methylethyl ester;APD 668; APD-668;CS-1179
Price26 Properties Safety Information Description
26 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0016CT
  • Product descriptionCID11705608
  • Packaging10mg
  • Price$502
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging1mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging5mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging10mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging25mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging50mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging100mg
  • Price$328
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging250mg
  • Price$547
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA603162
  • Product descriptionApd668 98+%
  • Packaging1g
  • Price$1336
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4671
  • Product descriptionAPD668
  • Packaging10mM(in 1mL DMSO)
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4671
  • Product descriptionAPD668
  • Packaging10mg
  • Price$253
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4671
  • Product descriptionAPD668
  • Packaging50mg
  • Price$829
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4671
  • Product descriptionAPD668
  • Packaging100mg
  • Price$1365
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17642
  • Product descriptionAPD668 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17642
  • Product descriptionAPD668 ≥98%
  • Packaging5mg
  • Price$202
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17642
  • Product descriptionAPD668 ≥98%
  • Packaging10mg
  • Price$363
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0016CT CID11705608 10mg $502 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 1mg $58 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 5mg $115 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 10mg $149 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 25mg $194 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 50mg $252 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 100mg $328 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 250mg $547 2021-12-16 Buy
Ambeed A603162 Apd668 98+% 1g $1336 2021-12-16 Buy
ApexBio Technology B4671 APD668 10mM(in 1mL DMSO) $133 2021-12-16 Buy
ApexBio Technology B4671 APD668 10mg $253 2021-12-16 Buy
ApexBio Technology B4671 APD668 50mg $829 2021-12-16 Buy
ApexBio Technology B4671 APD668 100mg $1365 2021-12-16 Buy
Cayman Chemical 17642 APD668 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 17642 APD668 ≥98% 5mg $202 2024-03-01 Buy
Cayman Chemical 17642 APD668 ≥98% 10mg $363 2024-03-01 Buy
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Properties

Boiling point :611.6±55.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥17.4 mg/mL in DMSO; ≥2.61 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :2.13±0.30(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GPR119, a glucose-dependent insulinotropic receptor, is a G protein-coupled receptor that is expressed in pancreatic β-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine increases intracellular cAMP levels and promotes glucose-stimulated insulin secretion. APD668 is a potent agonist of GPR119 (EC50s = 2.7 and 33 nM for human and rat forms, respectively). Chronic dosing with APD668 in Zucker diabetic fatty rats over several weeks significantly reduces blood glucose and glycated hemoglobin levels.

Suppliers and manufacturers

career henan chemical co
ISOPROPYL 4-(1-(2-FLUORO-4-(METHYLSULFONYL)PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLOXY)PIPERIDINE-1-CARBOXYLATE
$1.00 /1ASSAYS
ISOPROPYL 4-(1-(2-FLUORO-4-(METHYLSULFONYL)PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLOXY)PIPERIDINE-1-CARBOXYLATE CAS:832714-46-2
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