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ChemicalBook >> CAS DataBase List >> Abiraterone

Abiraterone

Abiraterone price.
  • $28 - $2680
  • Product name: Abiraterone
  • CAS: 154229-19-3
  • MF: C24H31NO
  • MW: 349.52
  • EINECS:810-941-6
  • MDL Number:MFCD00924100
  • Synonyms:abiraterone;Cb 7598;Unii-G819A456D0;Abiraterone(CB-7598);17-(3-Pyridyl)androsta-5,16-dien-3beta-ol;Aberration;ABT 17-(3-pyridyl)androsta-5,16-dien-3β-ol abiraterone;(3b)-17-(3-pyridinyl)-Androsta-5,16-dien-3-ol
44 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Chemtos
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 1unit
  • 2.5MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 2x50mg
  • 10mM(in 1mL DMSO)
  • 200mg
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  • 500mg
  • 1g
  • 2g
  • 5g
  • ManufacturerAK Scientific
  • Product numberJ97499
  • Product descriptionAbiraterone
  • Packaging5g
  • Price$230
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006431
  • Product descriptionABIRATERONE 95.00%
  • Packaging2.5MG
  • Price$770
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4240
  • Product descriptionAbiraterone
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4240
  • Product descriptionAbiraterone
  • Packaging5mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4240
  • Product descriptionAbiraterone
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4240
  • Product descriptionAbiraterone
  • Packaging50mg
  • Price$143
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1873
  • Product descriptionAbiraterone-CB7598 100%
  • Packaging2x50mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180806
  • Product descriptionAbiraterone (CB-7598) >99%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb180806
  • Product descriptionAbiraterone (CB-7598) >99%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb180806
  • Product descriptionAbiraterone (CB-7598) >99%
  • Packaging1g
  • Price$1208.7
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBA164060
  • Product descriptionAbiraterone
  • Packaging10mg
  • Price$54
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16899
  • Product descriptionAbiraterone
  • Packaging250mg
  • Price$62.5
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBA164060
  • Product descriptionAbiraterone
  • Packaging100mg
  • Price$86
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16899
  • Product descriptionAbiraterone
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16899
  • Product descriptionAbiraterone
  • Packaging1g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA16899
  • Product descriptionAbiraterone
  • Packaging2g
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J97499 Abiraterone 5g $230 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006431 ABIRATERONE 95.00% 2.5MG $770 2021-12-16 Buy
ApexBio Technology A4240 Abiraterone 1unit $28 2021-12-16 Buy
ApexBio Technology A4240 Abiraterone 5mg $36 2021-12-16 Buy
ApexBio Technology A4240 Abiraterone 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A4240 Abiraterone 50mg $143 2021-12-16 Buy
Axon Medchem Axon1873 Abiraterone-CB7598 100% 2x50mg $440 2021-12-16 Buy
Biorbyt Ltd orb180806 Abiraterone (CB-7598) >99% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb180806 Abiraterone (CB-7598) >99% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb180806 Abiraterone (CB-7598) >99% 1g $1208.7 2021-12-16 Buy
Biosynth Carbosynth BA164060 Abiraterone 10mg $54 2021-12-16 Buy
Biosynth Carbosynth FA16899 Abiraterone 250mg $62.5 2021-12-16 Buy
Biosynth Carbosynth BA164060 Abiraterone 100mg $86 2021-12-16 Buy
Biosynth Carbosynth FA16899 Abiraterone 500mg $100 2021-12-16 Buy
Biosynth Carbosynth FA16899 Abiraterone 1g $150 2021-12-16 Buy
Biosynth Carbosynth FA16899 Abiraterone 2g $250 2021-12-16 Buy

Properties

Melting point :227-228 °C(Solv: toluene (108-88-3))
Boiling point :500.2±50.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :14.71±0.70(Predicted)
color :White to Pale Yellow
CAS DataBase Reference :154229-19-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304 IF INHALED:
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P340 Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362 Take off contaminated clothing and wash before reuse.
P403 Store in a well-ventilated place.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Abiraterone is a new type of hormone therapy. It is also called abiraterone acetate, CB7630 or Zytiga. It is used to treat prostate cancer that has spread to other parts of the body. It may help some men to live longer. It can also help control symptoms. Clinical trials are also using abiraterone for earlier stages of prostate cancer and advanced breast cancer. Abiraterone is associated with a not uncommon rate of serum enzyme elevation during therapy, but has not been clearly linked to cases of clinically apparent liver injury with jaundice.

On April 28, 2011, the U.S. Food and Drug Administration approved abiraterone acetate (Zytiga Tablets, Centocor Ortho Biotech, Inc.) for use in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) who have received prior chemotherapy containing docetaxel.

Abiraterone is a steroidal compound with antiandrogen activity. it is a Cytochrome P450 17A1 Inhibitor. The mechanism of action of abiraterone is as a Cytochrome P450 17A1 Inhibitor, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 2C8 Inhibitor that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
Zytiga (abiraterone acetate)
figure 1: Zytiga (abiraterone acetate)

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