Apatinib
|
- $49 - $1315
- Product name: Apatinib
- CAS: 811803-05-1
- MF: C24H23N5O
- MW: 397.47
- EINECS:1592732-453-0
- MDL Number:MFCD22420814
- Synonyms:Apatinib;Apatinib (YN968D1);Aptinib;N-(4-(1-cyanocyclopentyl)phenyl)-2-(pyridin-4-ylMethylaMino)nicotinaMide;Mesylate APA;N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide Apatinib;3-Pyridinecarboxamide, N-[4-(1-cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-;CS-1160
26 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- AvaChem
- Biosynth
- Cayman Chemical
- Chemenu
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 5mg
- 10mg
- 50mg
- 25MG
- 100MG
- 10mM*1mLinDMSO
- 250mg
- 1.00g
- 1G
- ManufacturerACHEMBLOCK
- Product number10267
- Product descriptionApatinib 98%
- Packaging25MG
- Price$65
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10267
- Product descriptionApatinib 98%
- Packaging100MG
- Price$195
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10267
- Product descriptionApatinib 98%
- Packaging1G
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ97254
- Product descriptionApatinib
- Packaging100mg
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3006B
- Product descriptionApatinib 98%
- Packaging5mg
- Price$49
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number3006B
- Product descriptionApatinib 98%
- Packaging25mg
- Price$105
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number3006B
- Product descriptionApatinib 98%
- Packaging100mg
- Price$225
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number3006B
- Product descriptionApatinib 98%
- Packaging250mg
- Price$435
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number3006B
- Product descriptionApatinib 98%
- Packaging1g
- Price$1275
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberBA175030
- Product descriptionApatinib
- Packaging100mg
- Price$866
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA175030
- Product descriptionApatinib
- Packaging25mg
- Price$384.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA175030
- Product descriptionApatinib
- Packaging50mg
- Price$576.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA175030
- Product descriptionApatinib
- Packaging10mg
- Price$192.3
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number21268
- Product descriptionApatinib ≥98%
- Packaging10mg
- Price$194
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21268
- Product descriptionApatinib ≥98%
- Packaging5mg
- Price$103
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21268
- Product descriptionApatinib ≥98%
- Packaging25mg
- Price$502
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | 10267 | Apatinib 98% | 25MG | $65 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10267 | Apatinib 98% | 100MG | $195 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10267 | Apatinib 98% | 1G | $650 | 2026-05-27 | Buy |
| AK Scientific | J97254 | Apatinib | 100mg | $195 | 2021-12-16 | Buy |
| AvaChem | 3006B | Apatinib 98% | 5mg | $49 | 2026-05-22 | Buy |
| AvaChem | 3006B | Apatinib 98% | 25mg | $105 | 2026-05-22 | Buy |
| AvaChem | 3006B | Apatinib 98% | 100mg | $225 | 2026-05-22 | Buy |
| AvaChem | 3006B | Apatinib 98% | 250mg | $435 | 2026-05-22 | Buy |
| AvaChem | 3006B | Apatinib 98% | 1g | $1275 | 2026-05-22 | Buy |
| Biosynth | BA175030 | Apatinib | 100mg | $866 | 2026-06-04 | Buy |
| Biosynth | BA175030 | Apatinib | 25mg | $384.5 | 2026-06-04 | Buy |
| Biosynth | BA175030 | Apatinib | 50mg | $576.5 | 2026-06-04 | Buy |
| Biosynth | BA175030 | Apatinib | 10mg | $192.3 | 2026-06-04 | Buy |
| Cayman Chemical | 21268 | Apatinib ≥98% | 10mg | $194 | 2026-04-30 | Buy |
| Cayman Chemical | 21268 | Apatinib ≥98% | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 21268 | Apatinib ≥98% | 25mg | $502 | 2026-04-30 | Buy |
Properties
Boiling point :578.2±50.0 °C(Predicted)
Density :1.27
storage temp. :Store at -20°C
solubility :>49.4mg/ml in DMSO
form :Powder
pka :11.93±0.70(Predicted)
color :white to beige
Appearance :white solid
Density :1.27
storage temp. :Store at -20°C
solubility :>49.4mg/ml in DMSO
form :Powder
pka :11.93±0.70(Predicted)
color :white to beige
Appearance :white solid
Safety Information
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Description
Apatinib mesylate, discovered by Advenchen Laboratories (United States of America, USA) and co-developed by Jiangsu Hengrui Medicine Co. Ltd (China), was approved by the Chinese Food and Drug Administration (CFDA) in October 2014 for the treatment of metastatic gastric carcinoma. Apatinib mesylate is an oral tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor 2 (VEGFR2), which prevents new blood vessel formation selectively in tumor tissue. Apatinib has shown inhibition of the VEGF signaling pathway with an IC50 value of 1 nM for VEGFR-2 in in vitro enzyme experiments. A multicenter phase II study of apatinib is underway with patients in non-triple-negative metastatic breast cancer trials. Non-clinical studies concluded that apatinib may reverse the ATP-binding cassette subfamily B member 1 and subfamily G member 2 (ABCB1- and ABCG2, respectively)-mediated multidrug resistance which allows cancer cells to circumvent certain conventional antineoplastic drugs, suggesting that apatinib could be effective as a combination therapy.More related product prices
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