CAY10574
|
- $28 - $3224
- Product name: CAY10574
- CAS: 140651-18-9
- MF: C9H10N6O
- MW: 218.22
- EINECS:
- MDL Number:MFCD09262258
- Synonyms:CAY10574;Cdk9 Inhibitor II;4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol;CAN-508 (CAN508);CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem;inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,adenocarcinoma,HT-29,CAN-508;Phenol, 4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazenyl]-;4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol
27 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA001CK3
- Product description4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol ≥95%
- Packaging1mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001CK3
- Product description4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol
- Packaging5mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001CK3
- Product description4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol
- Packaging10mg
- Price$53
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001CK3
- Product description4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol
- Packaging25mg
- Price$91
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001CK3
- Product description4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol
- Packaging50mg
- Price$127
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001CK3
- Product description4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol
- Packaging100mg
- Price$179
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY232463
- Product descriptionCAN508 98%
- Packaging100MG
- Price$275
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY232463
- Product descriptionCAN508 98%
- Packaging1G
- Price$870
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1666AH
- Product descriptionCDK9inhibitorII
- Packaging50mg
- Price$997
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1666AH
- Product descriptionCDK9inhibitorII
- Packaging1mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberQFA65118
- Product descriptionCdk9 Inhibitor II
- Packaging10mg
- Price$671.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberQFA65118
- Product descriptionCdk9 Inhibitor II
- Packaging25mg
- Price$1259.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberQFA65118
- Product descriptionCdk9 Inhibitor II
- Packaging50mg
- Price$2014.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberQFA65118
- Product descriptionCdk9 Inhibitor II
- Packaging100mg
- Price$3224
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number10011247
- Product descriptionCAY10574 ≥95%
- Packaging50mg
- Price$888
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10011247
- Product descriptionCAY10574 ≥95%
- Packaging10mg
- Price$205
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001CK3 | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol ≥95% | 1mg | $28 | 2026-05-28 | Buy |
| aablocks | AA001CK3 | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | 5mg | $44 | 2026-05-28 | Buy |
| aablocks | AA001CK3 | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | 10mg | $53 | 2026-05-28 | Buy |
| aablocks | AA001CK3 | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | 25mg | $91 | 2026-05-28 | Buy |
| aablocks | AA001CK3 | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | 50mg | $127 | 2026-05-28 | Buy |
| aablocks | AA001CK3 | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | 100mg | $179 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y232463 | CAN508 98% | 100MG | $275 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y232463 | CAN508 98% | 1G | $870 | 2026-05-27 | Buy |
| AK Scientific | 1666AH | CDK9inhibitorII | 50mg | $997 | 2021-12-16 | Buy |
| AK Scientific | 1666AH | CDK9inhibitorII | 1mg | $125 | 2021-12-16 | Buy |
| Biosynth | QFA65118 | Cdk9 Inhibitor II | 10mg | $671.5 | 2026-06-04 | Buy |
| Biosynth | QFA65118 | Cdk9 Inhibitor II | 25mg | $1259.25 | 2026-06-04 | Buy |
| Biosynth | QFA65118 | Cdk9 Inhibitor II | 50mg | $2014.5 | 2026-06-04 | Buy |
| Biosynth | QFA65118 | Cdk9 Inhibitor II | 100mg | $3224 | 2026-06-04 | Buy |
| Cayman Chemical | 10011247 | CAY10574 ≥95% | 50mg | $888 | 2026-04-30 | Buy |
| Cayman Chemical | 10011247 | CAY10574 ≥95% | 10mg | $205 | 2026-04-30 | Buy |
Properties
Boiling point :638.3±55.0 °C(Predicted)
Density :1.67±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMF: 0.5 mg/ml; DMSO: 0.5 mg/ml
pka :8.52±0.30(Predicted)
form :Yellow semi-solid
color :Light yellow to yellow
InChI :1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)
InChIKey :AYZRKFOEZQBUEA-UHFFFAOYSA-N
SMILES :[nH]1nc(c(c1N)N=Nc2ccc(cc2)O)N
Density :1.67±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMF: 0.5 mg/ml; DMSO: 0.5 mg/ml
pka :8.52±0.30(Predicted)
form :Yellow semi-solid
color :Light yellow to yellow
InChI :1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)
InChIKey :AYZRKFOEZQBUEA-UHFFFAOYSA-N
SMILES :[nH]1nc(c(c1N)N=Nc2ccc(cc2)O)N
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Cdk9 Inhibitor II is an ATP-competitive inhibitor of cyclin-dependent kinase 9 (Cdk9; IC50 = 350 nM) and moderate inhibitor of similar enzymes including Cdk2-cyclin E. In the HT-29 cancer cell line, Cdk9 inhibitor II was observed to attenuate the frequency of the S-phase. Other Cdk9 Inhibitor II effects were shown to involve inhibition of mRNA synthesis, induction of p53, inhibition of IL-6 signaling and reduced phosphorylation of both retinoblastoma protein and RNA polymerase II at the C-terminal domain. Cdk9 Inhibitor II has been observed to be an effective antitumor and antimetastatic agent by disrupting TNFα signaling. Cdk9 Inhibitor II is an inhibitor of Cdk4, cyclin D1 and p70 S6 Kinase.Related product price
-
NU6102
$40-2572.5 -
BMS-265246
$17-2600 -
741713-40-6
$54-3200
