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ChemicalBook >> CAS DataBase List >> CAY10703

CAY10703

CAY10703 price.
  • $32 - $533
  • Product name: CAY10703
  • CAS: 1841421-67-7
  • MF: C12H18Cl6N4O3
  • MW: 479.01
  • EINECS:
  • MDL Number:MFCD31735847
  • Synonyms:CAY10703;CAY10703,CAY-10703;Acetamide, N,N',N''-(nitrilotri-2,1-ethanediyl)tris[2,2-dichloro-;N,N',N''-(nitrilotris(ethane-2,1-diyl))tris(2,2-dichloroacetamide)
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number7562EH
  • Product descriptionN-[2-[Bis[2-[(2,2-dichloroacetyl)amino]ethyl]amino]ethyl]-2,2-dichloroacetamide
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18911
  • Product descriptionCAY10703 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18911
  • Product descriptionCAY10703 ≥95%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18911
  • Product descriptionCAY10703 ≥95%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18911
  • Product descriptionCAY10703 ≥95%
  • Packaging25mg
  • Price$533
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7562EH N-[2-[Bis[2-[(2,2-dichloroacetyl)amino]ethyl]amino]ethyl]-2,2-dichloroacetamide 10mg $370 2021-12-16 Buy
Cayman Chemical 18911 CAY10703 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 18911 CAY10703 ≥95% 5mg $139 2024-03-01 Buy
Cayman Chemical 18911 CAY10703 ≥95% 10mg $243 2024-03-01 Buy
Cayman Chemical 18911 CAY10703 ≥95% 25mg $533 2024-03-01 Buy

Properties

Boiling point :680.0±55.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :11.84±0.46(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Dichloroacetate (DCA) is an inhibitor of all pyruvate dehydrogenase kinase (PDHK) isoforms, which are enzymes that phosphorylate and inhibit PDH in mitochondria. Inhibition of PDHK shifts cell metabolism from glycolysis to mitochondrial glucose oxidation, an effect that has relevance to cancer, type 2 diabetes, and other diseases. CAY10703 is a DCA trimer that is at least 10-fold more cytotoxic against leukemia cell lines than DCA. It is approximately 3-fold less cytotoxic than DCA against peripheral blood mononuclear cells from healthy blood donors. CAY10703 significantly reduces both basal and maximal respiration in leukemia cells. It is stable in vivo after subcutaneous inoculation, remaining in circulation for more than five hours after injection.