CID 16020046
|
- $36 - $1800
- Product name: CID 16020046
- CAS: 834903-43-4
- MF: C25H19N3O4
- MW: 425.44
- EINECS:
- MDL Number:MFCD06196075
- Synonyms:4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid;CID 16020046;4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid;CID16020046 (CID 16020046);Benzoic acid, 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-;CS-1189;CID16020046;CID 16020046;CID 16020046;C390-0219
22 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 25
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number3545AH
- Product descriptionCID16020046
- Packaging100mg
- Price$937
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA843612
- Product descriptionCID-16020046 98+%
- Packaging5mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA843612
- Product descriptionCID-16020046 98+%
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA843612
- Product descriptionCID-16020046 98+%
- Packaging25mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA843612
- Product descriptionCID-16020046 98+%
- Packaging50mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004958
- Product descriptionCID-16020046 95.00%
- Packaging5MG
- Price$458.88
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15247
- Product descriptionCID16020046 ≥98%
- Packaging1mg
- Price$36
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15247
- Product descriptionCID16020046 ≥98%
- Packaging5mg
- Price$112
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15247
- Product descriptionCID16020046 ≥98%
- Packaging10mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15247
- Product descriptionCID16020046 ≥98%
- Packaging25mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3230
- Product descriptionCID16020046 99.92%
- Packaging10mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3230
- Product descriptionCID16020046 99.92%
- Packaging50mg
- Price$748
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000686
- Product descriptionCID16020046 98+%
- Packaging25mg
- Price$312
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000686
- Product descriptionCID16020046 98+%
- Packaging50mg
- Price$592
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10873
- Product descriptionCID16020046 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10873
- Product descriptionCID16020046 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3545AH | CID16020046 | 100mg | $937 | 2021-12-16 | Buy |
| Ambeed | A843612 | CID-16020046 98+% | 5mg | $73 | 2021-12-16 | Buy |
| Ambeed | A843612 | CID-16020046 98+% | 10mg | $95 | 2021-12-16 | Buy |
| Ambeed | A843612 | CID-16020046 98+% | 25mg | $124 | 2021-12-16 | Buy |
| Ambeed | A843612 | CID-16020046 98+% | 50mg | $162 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004958 | CID-16020046 95.00% | 5MG | $458.88 | 2021-12-16 | Buy |
| Cayman Chemical | 15247 | CID16020046 ≥98% | 1mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 15247 | CID16020046 ≥98% | 5mg | $112 | 2024-03-01 | Buy |
| Cayman Chemical | 15247 | CID16020046 ≥98% | 10mg | $172 | 2024-03-01 | Buy |
| Cayman Chemical | 15247 | CID16020046 ≥98% | 25mg | $341 | 2024-03-01 | Buy |
| ChemScene | CS-3230 | CID16020046 99.92% | 10mg | $178 | 2021-12-16 | Buy |
| ChemScene | CS-3230 | CID16020046 99.92% | 50mg | $748 | 2021-12-16 | Buy |
| Crysdot | CD31000686 | CID16020046 98+% | 25mg | $312 | 2021-12-16 | Buy |
| Crysdot | CD31000686 | CID16020046 98+% | 50mg | $592 | 2021-12-16 | Buy |
| DC Chemicals | DC10873 | CID16020046 >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC10873 | CID16020046 >98% | 1g | $1800 | 2021-12-16 | Buy |
Properties
Boiling point :748.1±60.0 °C(Predicted)
Density :1.425±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
pka :4.27±0.10(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C25H19N3O4/c1-14-5-7-15(8-6-14)21-20-22(27-26-21)24(30)28(18-11-9-16(10-12-18)25(31)32)23(20)17-3-2-4-19(29)13-17/h2-13,23,29H,1H3,(H,26,27)(H,31,32)
InChIKey :VGUQVYZXABOXCX-UHFFFAOYSA-N
SMILES :C(O)(=O)C1=CC=C(N2C(C3=CC=CC(O)=C3)C3C(C4=CC=C(C)C=C4)=NNC=3C2=O)C=C1
Density :1.425±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
pka :4.27±0.10(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C25H19N3O4/c1-14-5-7-15(8-6-14)21-20-22(27-26-21)24(30)28(18-11-9-16(10-12-18)25(31)32)23(20)17-3-2-4-19(29)13-17/h2-13,23,29H,1H3,(H,26,27)(H,31,32)
InChIKey :VGUQVYZXABOXCX-UHFFFAOYSA-N
SMILES :C(O)(=O)C1=CC=C(N2C(C3=CC=CC(O)=C3)C3C(C4=CC=C(C)C=C4)=NNC=3C2=O)C=C1
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
GPR55 is a G protein-coupled receptor (GPCR) that is weakly activated by some cannabinoids (CBs) at nM concentrations but displays a 5- to 10-fold greater stimulation in response to 1 μM lysophosphatidylinositol (LPI). CID16020046 is a GPR55 inverse agonist that antagonizes GPR55 constitutive activity with an IC50 value of 15 μM. It inhibits GPR55-mediated ERK1/2 phosphorylation, LPI-induced Ca2+ signaling (IC50 = 0.21 μM in HEK-GPR55 cells), and GPR55-mediated transcription factor activation. It does not affect ERK1/2 phosphorylation or transcription factor activation in CB receptor expressing cells and demonstrates weak activity against a broad spectrum of other GPCRs, ion channels, kinases, and nuclear receptors. This compound has been shown to block GPR55-mediated endothelial wound healing and reverse LPI-inhibited platelet aggregation.Related product price
- Diphenylphosphine oxide
$8-44550 - Uracil
$5-631
