CID-49830258
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- $14 - $1700
- Product name: CID-49830258
- CAS: 1346527-98-7
- MF: C23H20N6O
- MW: 396.44
- EINECS:
- MDL Number:MFCD28137687
- Synonyms:2-(2-Amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine;CID-49830258;ML240;2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine;2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine;CS-2775;ML240, >98%;4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 50
- 1G
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA009CKG
- Product descriptionML240 98+%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKG
- Product descriptionML240 98+%
- Packaging5mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKG
- Product descriptionML240 ≥99%(HPLC)
- Packaging10mg
- Price$51
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKG
- Product descriptionML240 ≥99%(HPLC)
- Packaging25mg
- Price$86
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKG
- Product descriptionML240 ≥99%(HPLC)
- Packaging50mg
- Price$147
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKG
- Product descriptionML240 ≥99%(HPLC)
- Packaging100mg
- Price$248
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33802
- Product descriptionML240 98%
- Packaging100MG
- Price$220
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33802
- Product descriptionML240 98%
- Packaging1G
- Price$1310
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5296
- Product descriptionML240
- Packaging50mg
- Price$634
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5296
- Product descriptionML240
- Packaging100mg
- Price$1083
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML 240
- Packaging50mg
- Price$623
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML 240
- Packaging25mg
- Price$363
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML 240
- Packaging10mg
- Price$173
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML 240
- Packaging5mg
- Price$108
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-19795
- Product descriptionML240 99.87%
- Packaging10mg
- Price$132
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19795
- Product descriptionML240 99.87%
- Packaging5mg
- Price$88
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009CKG | ML240 98+% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA009CKG | ML240 98+% | 5mg | $28 | 2026-05-28 | Buy |
| aablocks | AA009CKG | ML240 ≥99%(HPLC) | 10mg | $51 | 2026-05-28 | Buy |
| aablocks | AA009CKG | ML240 ≥99%(HPLC) | 25mg | $86 | 2026-05-28 | Buy |
| aablocks | AA009CKG | ML240 ≥99%(HPLC) | 50mg | $147 | 2026-05-28 | Buy |
| aablocks | AA009CKG | ML240 ≥99%(HPLC) | 100mg | $248 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33802 | ML240 98% | 100MG | $220 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33802 | ML240 98% | 1G | $1310 | 2026-05-27 | Buy |
| AK Scientific | SYN5296 | ML240 | 50mg | $634 | 2021-12-16 | Buy |
| AK Scientific | SYN5296 | ML240 | 100mg | $1083 | 2021-12-16 | Buy |
| ApexBio Technology | B4926 | ML 240 | 50mg | $623 | 2026-05-06 | Buy |
| ApexBio Technology | B4926 | ML 240 | 25mg | $363 | 2026-05-06 | Buy |
| ApexBio Technology | B4926 | ML 240 | 10mg | $173 | 2026-05-06 | Buy |
| ApexBio Technology | B4926 | ML 240 | 5mg | $108 | 2026-05-06 | Buy |
| Arctom | HY-19795 | ML240 99.87% | 10mg | $132 | 2026-05-26 | Buy |
| Arctom | HY-19795 | ML240 99.87% | 5mg | $88 | 2026-05-26 | Buy |
Properties
Boiling point :696.6±65.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4.53±0.10(Predicted)
color :white to yellow to light brown
InChI :1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28)
InChIKey :NHAMBLRUUJAFOY-UHFFFAOYSA-N
SMILES :NC1=NC2=C(C=CC=C2)N1C3=NC4=C(OC)C=CC=C4C(NCC5=CC=CC=C5)=N3
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4.53±0.10(Predicted)
color :white to yellow to light brown
InChI :1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28)
InChIKey :NHAMBLRUUJAFOY-UHFFFAOYSA-N
SMILES :NC1=NC2=C(C=CC=C2)N1C3=NC4=C(OC)C=CC=C4C(NCC5=CC=CC=C5)=N3
Safety Information
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Description
The p97 AAA (ATPase associated with diverse cellular activities) uses energy from ATP hydrolysis to unfold proteins or disassemble protein complexes. p97 is a hexameric protein consisting of two AAA domains (D1 and D2) that form two stacked rings and an N-terminal domain that recruits cofactor/substrate specificity factors. It functions in many regulatory processes to maintain protein homeostasis and has become a therapeutic target for cancer and neurodegenerative diseases. ML-240 is an ATP-competitive inhibitor of the D2 domain of the p97 ATPase (IC50 = 0.11 μM; Ki = 0.22 μM). It disrupts the endoplasmic reticulum-associated degradation and autophagy pathways, preventing the degradation of p97-dependent proteasome substrates (IC50 = 0.9 μM) and causing accumulation of ubiquitin conjugates in nuclear membrane and cytosolic compartments at 5-10 μM. ML-240 has also been shown to block proliferation of HCT15 and SW403 colon cancer cell lines (GI50s = 0.76 and 0.5 μM, respectively) and to rapidly mobilize caspase-3 and -7, inducing apoptosis.More related product prices
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Suppliers and manufacturers
BOC Sciences
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Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Shanghai Chaolan Chemical Technology Center