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ChemicalBook >> CAS DataBase List >> DOFETILIDE-D4

DOFETILIDE-D4

DOFETILIDE-D4 price.
  • $153 - $1455
  • Product name: DOFETILIDE-D4
  • CAS: 1189700-56-8
  • MF: C19H27N3O5S2
  • MW: 441.56478
  • EINECS:
  • MDL Number:MFCD09840517
  • Synonyms:DOFETILIDE-D4; UK-68798-d4;N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide-d4;Tikosyn-d;Tikosyn-d4;UK 68789 D4;Dofetilide D4Q: What is Dofetilide D4 Q: What is the CAS Number of Dofetilide D4 Q: What is the storage condition of Dofetilide D4 Q: What are the applications of Dofetilide D4;N-[4-(2-{[2-(4-methanesulfonamidophenoxy)(1,1,2,2-2H?)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
Price6 Properties Safety Information Description
6 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 500μg
  • 1mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number5535DF
  • Product descriptionDofetilideD4
  • Packaging1mg
  • Price$421
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26451
  • Product descriptionDofetilide-d4
  • Packaging500μg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26451
  • Product descriptionDofetilide-d4
  • Packaging1mg
  • Price$290
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product numberD3782
  • Product descriptionDofetilide-d4 98%
  • Packaging1mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD525702
  • Product descriptionDofetilide-d4
  • Packaging10mg
  • Price$1455
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberD8079-25C
  • Product descriptionDofetilide-d4
  • Packaging1mg
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5535DF DofetilideD4 1mg $421 2021-12-16 Buy
Cayman Chemical 26451 Dofetilide-d4 500μg $153 2024-03-01 Buy
Cayman Chemical 26451 Dofetilide-d4 1mg $290 2024-03-01 Buy
Medical Isotopes, Inc. D3782 Dofetilide-d4 98% 1mg $950 2021-12-16 Buy
TRC D525702 Dofetilide-d4 10mg $1455 2021-12-16 Buy
Usbiological D8079-25C Dofetilide-d4 1mg $460 2021-12-16 Buy

Properties

Melting point :130-1350C
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White
CAS DataBase Reference :1189700-56-8

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Dofetilide-d4 is intended for use as an internal standard for the quantification of dofetilide by GC- or LC-MS. Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg. Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Dofetilide D4
$727.00 /1mg
Dofetilide D4 CAS:1189700-56-8
TargetMol Chemicals Inc. Chemsky（shanghai）International Co.,Ltd. Artis Biotech Co. Ltd. Clearsynth Canada Inc. Shenzhen SUNGENING Bio-Medical Co., Ltd. Chengdu Novel Biomedical Co., Ltd. Shanghai ring qi biological technology co., LTD Shenzhen Polymeri Biochemical Technology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd.