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ChemicalBook >> CAS DataBase List >> Dimethyl sulfate

Dimethyl sulfate

Dimethyl sulfate price.
  • $22 - $2743.13
  • Product name: Dimethyl sulfate
  • CAS: 77-78-1
  • MF: C2H6O4S
  • MW: 126.13
  • EINECS:201-058-1
  • MDL Number:MFCD00008416
  • Synonyms:sulfatededimethyle ;sulfatededimethyle(french) ;DIMETHYLSULFATE,REAGENT;Dimethylsulfate,98%;DIMETHYL SULFATE 99 % MIN.;DIMETHYL SULFATE MOLECULAR BIOLOGY*REAGE NT;DIMETHYL SULFATE 99+%;Dimethylsulphate99%
19 prices
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  • American Custom Chemicals Corporation
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • TRC
Package
  • 5MG
  • 1ml
  • 5ml
  • 10x1ml
  • 10ml
  • 10G
  • 25g
  • 100ml
  • 100G
  • 4x100ml
  • 500ml
  • 1l
  • 18L
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0029287
  • Product descriptionDIMETHYL SULFATE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0029287
  • Product descriptionDIMETHYL SULFATE 95.00%
  • Packaging10G
  • Price$1178.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0029287
  • Product descriptionDIMETHYL SULFATE 95.00%
  • Packaging100G
  • Price$2743.13
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number69799
  • Product descriptionDimethyl sulfate
  • Packaging100g
  • Price$875
  • Updated2021-12-16
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  • ManufacturerOakwood
  • Product number098977
  • Product descriptionDimethyl sulfate 95%
  • Packaging25g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number49497
  • Product descriptionDimethyl sulfate for GC derivatization, ≥99.0% (GC)
  • Packaging1ml
  • Price$25.8
  • Updated2022-05-15
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  • ManufacturerSigma-Aldrich
  • Product numberD186309
  • Product descriptionDimethyl sulfate ≥99.8%
  • Packaging5ml
  • Price$40.4
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product numberD186309
  • Product descriptionDimethyl sulfate ≥99.8%
  • Packaging100ml
  • Price$41.4
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product number41610
  • Product descriptionDimethyl sulfate puriss. p.a., ≥99.0% (GC)
  • Packaging100ml
  • Price$44.7
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product number49497
  • Product descriptionDimethyl sulfate for GC derivatization, ≥99.0% (GC)
  • Packaging10ml
  • Price$92.4
  • Updated2022-05-15
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  • ManufacturerSigma-Aldrich
  • Product number320293
  • Product descriptionDimethyl sulfate ≥99%
  • Packaging1l
  • Price$100
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product numberD186309
  • Product descriptionDimethyl sulfate ≥99.8%
  • Packaging500ml
  • Price$102
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number41610
  • Product descriptionDimethyl sulfate puriss. p.a., ≥99.0% (GC)
  • Packaging500ml
  • Price$108
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product numberD186309
  • Product descriptionDimethyl sulfate ≥99.5%
  • Packaging18L
  • Price$2740
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product numberD186309
  • Product descriptionDimethyl sulfate ≥99.8%
  • Packaging4x100ml
  • Price$150
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number41610
  • Product descriptionDimethyl sulfate puriss. p.a., ≥99.0% (GC)
  • Packaging1l
  • Price$156
  • Updated2024-03-01
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Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation CHM0029287 DIMETHYL SULFATE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation CHM0029287 DIMETHYL SULFATE 95.00% 10G $1178.1 2021-12-16 Buy
American Custom Chemicals Corporation CHM0029287 DIMETHYL SULFATE 95.00% 100G $2743.13 2021-12-16 Buy
Medical Isotopes, Inc. 69799 Dimethyl sulfate 100g $875 2021-12-16 Buy
Oakwood 098977 Dimethyl sulfate 95% 25g $22 2021-12-16 Buy
Sigma-Aldrich 49497 Dimethyl sulfate for GC derivatization, ≥99.0% (GC) 1ml $25.8 2022-05-15 Buy
Sigma-Aldrich D186309 Dimethyl sulfate ≥99.8% 5ml $40.4 2026-04-30 Buy
Sigma-Aldrich D186309 Dimethyl sulfate ≥99.8% 100ml $41.4 2026-04-30 Buy
Sigma-Aldrich 41610 Dimethyl sulfate puriss. p.a., ≥99.0% (GC) 100ml $44.7 2024-03-01 Buy
Sigma-Aldrich 49497 Dimethyl sulfate for GC derivatization, ≥99.0% (GC) 10ml $92.4 2022-05-15 Buy
Sigma-Aldrich 320293 Dimethyl sulfate ≥99% 1l $100 2026-04-30 Buy
Sigma-Aldrich D186309 Dimethyl sulfate ≥99.8% 500ml $102 2026-04-30 Buy
Sigma-Aldrich 41610 Dimethyl sulfate puriss. p.a., ≥99.0% (GC) 500ml $108 2024-03-01 Buy
Sigma-Aldrich D186309 Dimethyl sulfate ≥99.5% 18L $2740 2026-04-30 Buy
Sigma-Aldrich D186309 Dimethyl sulfate ≥99.8% 4x100ml $150 2026-04-30 Buy
Sigma-Aldrich 41610 Dimethyl sulfate puriss. p.a., ≥99.0% (GC) 1l $156 2024-03-01 Buy

Properties

Melting point :-32 °C
Boiling point :188 °C(lit.)
Density :1.333 g/mL at 25 °C(lit.)
vapor density :4.3 (vs air)
vapor pressure :0.7 mm Hg ( 25 °C)
refractive index :n20/D 1.386(lit.)
Flash point :182 °F
storage temp. :2-8°C
solubility :ethanol: 0.26 g/mL, clear, colorless
form :Liquid
color :Clear colorless
Odor :Almost odorless
explosive limit :3.6-23.2% (v/v)
Water Solubility :2.8 g/100 mL (18 ºC)
Merck :13,3282
BRN :635994
Henry's Law Constant :6.9×100 mol/(m3Pa) at 25℃, Hilal et al. (2008)
Exposure limits :TLV/PEL-TWA skin 0.1 ppm (0.52 mg/m3 ) (ACGIH, OSHA, NIOSH) IDLH 10 ppm (NIOSH).
Dielectric constant :55.0(20℃)
Stability :Stable; combustible. Incompatible with strong oxidizing agents, strong bases including ammonia. Moisture-sensitive.
InChI :1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3
InChIKey :VAYGXNSJCAHWJZ-UHFFFAOYSA-N
SMILES :COS(=O)(=O)OC
CAS DataBase Reference :77-78-1(CAS DataBase Reference)
IARC :2A (Vol. 4, Sup 7, 71) 1999
NIST Chemistry Reference :Sulfuric acid, dimethyl ester(77-78-1)
EPA Substance Registry System :Dimethyl sulfate (77-78-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Dimethyl sulfate (chemical formula: (CH3O)2SO2) is an odorless, corrosive, oily liquid which can release toxic fumes during heating. It can be synthesized through the esterification of sulfuric acid with methanol, and alternatively by the distillation of methyl hydrogen sulfate. In industry, dimethyl sulfate is used as a methylating agent for the manufacture of many organic chemicals. It can be used for methylation of phenols, amines, and thiol. Moreover, it can be used for base sequencing and DNA chain cleavage since it can rupture the imidazole rings present in guanine. It can also be used for protein-DNA interaction analysis. However, its vapor is toxic to eyes and lungs, can do harm to our body. It is a potential carcinogen based on known experimental data.

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