Dovitinib
|
- $92 - $6121.5
- Product name: Dovitinib
- CAS: 405169-16-6
- MF: C21H21FN6O
- MW: 392.43
- EINECS:1308068-626-2
- MDL Number:MFCD11870802
- Synonyms:4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one;dovitinib;Unii-I35H55G906;CHIR258 7.7G;TKI-258;4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one;CHIR-258(Dovitinib,TKI258);CHIR-258(Dovitinib)
30 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
Package
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 5G
- ManufacturerAK Scientific
- Product numberJ54360
- Product descriptionDovitinib
- Packaging25mg
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002571
- Product descriptionDOVITINIB 95.00%
- Packaging1MG
- Price$191.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002571
- Product descriptionDOVITINIB 95.00%
- Packaging5G
- Price$6121.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2168
- Product descriptionDovitinib(TKI-258,CHIR-258)
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60335
- Product descriptionDovitinib(TKI-258) ≥98%
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545990
- Product descriptionDovitinib >98%
- Packaging5mg
- Price$198.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545990
- Product descriptionDovitinib >98%
- Packaging25mg
- Price$489.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154678
- Product descriptionDovitinib (TKI258, CHIR258) >99%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154678
- Product descriptionDovitinib (TKI258, CHIR258) >99%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154678
- Product descriptionDovitinib (TKI258, CHIR258) >99%
- Packaging1g
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD22602
- Product descriptionDovitinib base
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD22602
- Product descriptionDovitinib base
- Packaging50mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15220
- Product descriptionDovitinib ≥98%
- Packaging5mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15220
- Product descriptionDovitinib ≥98%
- Packaging10mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15220
- Product descriptionDovitinib ≥98%
- Packaging25mg
- Price$313
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15220
- Product descriptionDovitinib ≥98%
- Packaging50mg
- Price$505
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J54360 | Dovitinib | 25mg | $199 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002571 | DOVITINIB 95.00% | 1MG | $191.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002571 | DOVITINIB 95.00% | 5G | $6121.5 | 2021-12-16 | Buy |
| ApexBio Technology | A2168 | Dovitinib(TKI-258,CHIR-258) | 25mg | $150 | 2021-12-16 | Buy |
| Arctom | CFN60335 | Dovitinib(TKI-258) ≥98% | 10mg | $138 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545990 | Dovitinib >98% | 5mg | $198.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545990 | Dovitinib >98% | 25mg | $489.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154678 | Dovitinib (TKI258, CHIR258) >99% | 100mg | $606.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154678 | Dovitinib (TKI258, CHIR258) >99% | 250mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154678 | Dovitinib (TKI258, CHIR258) >99% | 1g | $1802 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22602 | Dovitinib base | 10mg | $180 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22602 | Dovitinib base | 50mg | $500 | 2021-12-16 | Buy |
| Cayman Chemical | 15220 | Dovitinib ≥98% | 5mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 15220 | Dovitinib ≥98% | 10mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 15220 | Dovitinib ≥98% | 25mg | $313 | 2024-03-01 | Buy |
| Cayman Chemical | 15220 | Dovitinib ≥98% | 50mg | $505 | 2024-03-01 | Buy |
Properties
Density :1.386
storage temp. :-20°
solubility :Soluble in DMSO (up to 30 mg/ml).
form :solid
pka :9.44±0.70(Predicted)
color :Yellow-green
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference :405169-16-6
storage temp. :-20°
solubility :Soluble in DMSO (up to 30 mg/ml).
form :solid
pka :9.44±0.70(Predicted)
color :Yellow-green
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference :405169-16-6
Safety Information
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Description
Dovitinib is a receptor tyrosine kinase inhibitor that targets vascular endothelial growth factor-2, basic fibroblast growth factor-1, and platelet-derived growth factor β receptors (IC50s = 65, 11, and 5 nM, respectively). By impairing these kinase signals, 1 μM dovitinib has been shown to prevent the growth and motility of pancreatic cancer cell lines (HPAF-II, BxPC-3, MiaPaCa2, and L3.6pl). At 0.04 μM, dovitinib can inhibit endothelial cell proliferation and motility. These antiangiogenic effects have been proposed to be the mechanism by which dovitinib inhibits hepatocellular carcinoma growth and metastasis. Dovitinib has been evaluated in clinical trials for the treatment of advanced solid tumors.More related product prices
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4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one CAS:405169-16-6
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one CAS:405169-16-6