Gepirone
|
- $38 - $6808.73
- Product name: Gepirone
- CAS: 83928-76-1
- MF: C19H29N5O2
- MW: 359.47
- EINECS:807-662-7
- MDL Number:MFCD00868196
- Synonyms:GEPIRONE;4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione;4,4-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione;2,6-Piperidinedione, 4,4-dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-;Gepirona;Gepirona [spanish];Gepirone [inn];Gepirone er
42 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth
- Chemenu
- ChemScene
- Crysdot
- Matrix Scientific
- TRC
Package
- 5mg
- 10.00mg
- 10mg
- 25mg
- 25.00mg
- 50mg
- 50.00mg
- 100mg
- 250MG
- 1g
- 5G
- 10G
- Manufactureraablocks
- Product numberAA00G5JA
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99%
- Packaging5mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G5JA
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99%
- Packaging10mg
- Price$47
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G5JA
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99%
- Packaging25mg
- Price$58
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G5JA
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99%
- Packaging50mg
- Price$71
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G5JA
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99%
- Packaging100mg
- Price$94
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G5JA
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione ≥98%
- Packaging1g
- Price$800
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX186984
- Product description4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione 95%
- Packaging1G
- Price$1085
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX186984
- Product description4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione 95%
- Packaging250MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX186984
- Product description4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione 95%
- Packaging5G
- Price$4340
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2913AC
- Product description4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione
- Packaging1g
- Price$1023
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009194
- Product descriptionGEPIRONE 95.00%
- Packaging5G
- Price$4597.95
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009194
- Product descriptionGEPIRONE 95.00%
- Packaging10G
- Price$6808.73
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFO65115
- Product descriptionGepirone
- Packaging100mg
- Price$344
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFO65115
- Product descriptionGepirone
- Packaging50mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFO65115
- Product descriptionGepirone
- Packaging250mg
- Price$550
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFO65115
- Product descriptionGepirone
- Packaging10mg
- Price$150
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00G5JA | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99% | 5mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00G5JA | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99% | 10mg | $47 | 2026-05-28 | Buy |
| aablocks | AA00G5JA | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99% | 25mg | $58 | 2026-05-28 | Buy |
| aablocks | AA00G5JA | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99% | 50mg | $71 | 2026-05-28 | Buy |
| aablocks | AA00G5JA | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione 99% | 100mg | $94 | 2026-05-28 | Buy |
| aablocks | AA00G5JA | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione ≥98% | 1g | $800 | 2026-05-28 | Buy |
| ACHEMBLOCK | X186984 | 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione 95% | 1G | $1085 | 2026-05-27 | Buy |
| ACHEMBLOCK | X186984 | 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione 95% | 250MG | $295 | 2026-05-27 | Buy |
| ACHEMBLOCK | X186984 | 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione 95% | 5G | $4340 | 2026-05-27 | Buy |
| AK Scientific | 2913AC | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione | 1g | $1023 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009194 | GEPIRONE 95.00% | 5G | $4597.95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009194 | GEPIRONE 95.00% | 10G | $6808.73 | 2021-12-16 | Buy |
| Biosynth | FO65115 | Gepirone | 100mg | $344 | 2026-06-04 | Buy |
| Biosynth | FO65115 | Gepirone | 50mg | $225 | 2021-12-16 | Buy |
| Biosynth | FO65115 | Gepirone | 250mg | $550 | 2026-06-04 | Buy |
| Biosynth | FO65115 | Gepirone | 10mg | $150 | 2026-06-04 | Buy |
Properties
Melting point :106-108°C
Boiling point :562.3±60.0 °C(Predicted)
Density :1.142±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :7.72±0.10(Predicted)
color :Off-White to Pale Yellow
InChI :InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3
InChIKey :QOIGKGMMAGJZNZ-UHFFFAOYSA-N
SMILES :N1(CCCCN2CCN(C3=NC=CC=N3)CC2)C(=O)CC(C)(C)CC1=O
Boiling point :562.3±60.0 °C(Predicted)
Density :1.142±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :7.72±0.10(Predicted)
color :Off-White to Pale Yellow
InChI :InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3
InChIKey :QOIGKGMMAGJZNZ-UHFFFAOYSA-N
SMILES :N1(CCCCN2CCN(C3=NC=CC=N3)CC2)C(=O)CC(C)(C)CC1=O
Safety Information
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Description
Gepirone is a chemical analogue of buspirone and also acts as a partial agonist at 5-HT1A receptors. It is active in animal models predictive of anxiolytic action and also shows antidepressant activity in preclinical studies. With long-term administration, gepirone downregulates 5-HT2 receptors, which is a property common to nearly all antidepressant drugs (Stahl 1994). This dual action, suggesting both anxiolytic and antidepressant effects, is typical of many compounds acting at 5-HT1A receptors and may indicate that such compounds may be useful in the treatment of mixed anxiety and depression (Stahl, in press).Preliminary phase II clinical data have shown that gepirone is an effective anxiolytic that significantly reduces both psychic and somatic symptoms of generalized anxiety disorder. Like buspirone, gepirone does not impair memory, verbal fluency, or psychomotor performance (Harto and Branconnier 1988).
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