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ChemicalBook >> CAS DataBase List >> GS 441524

GS 441524

GS 441524 price.
  • $8 - $3781.25
  • Product name: GS 441524
  • CAS: 1191237-69-0
  • MF: C12H13N5O4
  • MW: 291.26
  • EINECS:200-001-8
  • MDL Number:MFCD32666994
  • Synonyms:2-C-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-2,5-ANHYDRO-3,4-O-(1-METHYLETHYLIDENE)-D-ALTRONONITRI;D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-;2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-Altrononitrile;GS441525;(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDRO;GS-441524(EVO984);Remdesivir Impurity 6;S-441524
80 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
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  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Synthonix
  • Tocris
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Package
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  • 10mM(1mLinDMSO)
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  • 0.25g
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  • 1g
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  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile ≥98%(HPLC)
  • Packaging5mg
  • Price$10
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98%
  • Packaging100mg
  • Price$11
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile ≥98%(HPLC)
  • Packaging10mg
  • Price$11
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98%
  • Packaging250mg
  • Price$16
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98%
  • Packaging1g
  • Price$27
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98%
  • Packaging5g
  • Price$108
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98%
  • Packaging10g
  • Price$198
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01FVYF
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98%
  • Packaging25g
  • Price$453
  • Updated2026-05-30
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  • ManufacturerACHEMBLOCK
  • Product numberU140425
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 95%
  • Packaging25G
  • Price$375
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberU140425
  • Product description(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 95%
  • Packaging5G
  • Price$125
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3722-M050
  • Product descriptionGS-441524 (Remdesivir Metabolite) ≥98%(HPLC)
  • Packaging50mg
  • Price$120
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3722-M050
  • Product descriptionGS-441524(RemdesivirMetabolite) ≥98%(HPLC)
  • Packaging50mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3722-M010
  • Product descriptionGS-441524 (Remdesivir Metabolite) ≥98%(HPLC)
  • Packaging10mg
  • Price$70
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3722-M010
  • Product descriptionGS-441524(RemdesivirMetabolite) ≥98%(HPLC)
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3722-M005
  • Product descriptionGS-441524 (Remdesivir Metabolite) ≥98%(HPLC)
  • Packaging5mg
  • Price$45
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product number0879AP
  • Product descriptionGS441524
  • Packaging25mg
  • Price$89
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile ≥98%(HPLC) 5mg $10 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98% 100mg $11 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile ≥98%(HPLC) 10mg $11 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98% 250mg $16 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98% 1g $27 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98% 5g $108 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98% 10g $198 2026-05-30 Buy
aablocks AA01FVYF (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 98% 25g $453 2026-05-30 Buy
ACHEMBLOCK U140425 (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 95% 25G $375 2026-05-27 Buy
ACHEMBLOCK U140425 (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 95% 5G $125 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-3722-M050 GS-441524 (Remdesivir Metabolite) ≥98%(HPLC) 50mg $120 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3722-M050 GS-441524(RemdesivirMetabolite) ≥98%(HPLC) 50mg $210 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3722-M010 GS-441524 (Remdesivir Metabolite) ≥98%(HPLC) 10mg $70 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3722-M010 GS-441524(RemdesivirMetabolite) ≥98%(HPLC) 10mg $80 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3722-M005 GS-441524 (Remdesivir Metabolite) ≥98%(HPLC) 5mg $45 2026-05-06 Buy
AK Scientific 0879AP GS441524 25mg $89 2021-12-16 Buy

Properties

Melting point :> 233° C (dec.)
Density :1.84±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :12.13±0.70(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :InChI=1/C12H13N5O4/c13-4-12(10(20)9(19)7(3-18)21-12)8-2-1-6-11(14)15-5-16-17(6)8/h1-2,5,7,9-10,18-20H,3H2,(H2,14,15,16)/t7-,9-,10-,12+/s3
InChIKey :BRDWIEOJOWJCLU-QHRJDZJMNA-N
SMILES :C([C@]1(C2=CC=C3C(=NC=NN23)N)[C@@H]([C@H](O)[C@@H](CO)O1)O)#N |&1:1,12,13,15,r|
CAS DataBase Reference :1191237-69-0

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GS-441524 is the active prodrug of the broad-spectrum antiviral Remdesivir. GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of viral RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production (RNA synthesis arrest), either by terminating RNA chains or causing mutations. It inhibits MERS-CoV or SARS-CoV-infected HAE cultures (EC50=74nM and 69nM) and murine hepatitis virus (MHV) (EC50=30nM). In vivo, remdesivir (25 and 50 mg/kg) reduces lung viral titers and prevents weight loss in a mouse model of SARS-CoV infection. Remdesivir is used as a treatment for Ebola virus disease and Marburg virus infections and other single-stranded RNA viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, Nipah virus, Hendra virus and the coronaviruses (including MERS and SARS viruses). Remdesivir is effective in the control of 2019-nCoV (COVID-19) infection in vitro. It now also has been studied as a potential treatment for SARS-CoV-2 infections.

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