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ChemicalBook >> CAS DataBase List >> GW311616A

GW311616A

GW311616A price.
  • $90 - $2924
  • Product name: GW311616A
  • CAS: 197890-44-1
  • MF: C19H32ClN3O4S
  • MW: 433.99
  • EINECS:
  • MDL Number:MFCD06411566
  • Synonyms:CS-1260;GW 311616A;GW-311616A;GW 311616A - GW 311616 hydrochloride;GW311616 hydrochloride,GW-311616 hydrochloride
Price34 Properties Safety Information Description
34 prices
Selected condition：
Brand
  • aablocks
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
Package
  • 10mM(in1mLDMSO)
  • 100mg
  • 10mM*1mLinDMSO(Solution)
  • 2mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • Manufactureraablocks
  • Product numberAA00ABHJ
  • Product descriptionGW311616 Hydrochloride ≥95%
  • Packaging1mg
  • Price$90
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHJ
  • Product descriptionGW311616 Hydrochloride ≥95%
  • Packaging5mg
  • Price$262
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHJ
  • Product descriptionGW311616 Hydrochloride ≥95%
  • Packaging10mg
  • Price$436
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHJ
  • Product descriptionGW311616 Hydrochloride 99%
  • Packaging25mg
  • Price$1030
  • Updated2026-05-28
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616 hydrochloride
  • Packaging50mg
  • Price$1705
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging10mM(in 1mL DMSO)
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616 hydrochloride
  • Packaging10mg
  • Price$550
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging100mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616 hydrochloride
  • Packaging5mg
  • Price$380
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616 hydrochloride
  • Packaging10mM(in1mLDMSO)
  • Price$385
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-15891A
  • Product descriptionGW311616hydrochloride 98.57%
  • Packaging5mg
  • Price$428
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15891A
  • Product descriptionGW311616hydrochloride 98.57%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$471
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15891A
  • Product descriptionGW311616hydrochloride 98.57%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$447
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15891A
  • Product descriptionGW311616hydrochloride 98.57%
  • Packaging10mg
  • Price$751
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15891A
  • Product descriptionGW311616hydrochloride 98.57%
  • Packaging25mg
  • Price$1653
  • Updated2026-05-26
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2364
  • Product descriptionGW 311616A 99%
  • Packaging25mg
  • Price$792
  • Updated2026-05-19
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABHJ GW311616 Hydrochloride ≥95% 1mg $90 2026-05-28 Buy
aablocks AA00ABHJ GW311616 Hydrochloride ≥95% 5mg $262 2026-05-28 Buy
aablocks AA00ABHJ GW311616 Hydrochloride ≥95% 10mg $436 2026-05-28 Buy
aablocks AA00ABHJ GW311616 Hydrochloride 99% 25mg $1030 2026-05-28 Buy
ApexBio Technology B4676 GW311616 hydrochloride 50mg $1705 2026-05-06 Buy
ApexBio Technology B4676 GW311616hydrochloride 10mM(in 1mL DMSO) $460 2021-12-16 Buy
ApexBio Technology B4676 GW311616 hydrochloride 10mg $550 2026-05-06 Buy
ApexBio Technology B4676 GW311616hydrochloride 100mg $210 2021-12-16 Buy
ApexBio Technology B4676 GW311616 hydrochloride 5mg $380 2026-05-06 Buy
ApexBio Technology B4676 GW311616 hydrochloride 10mM(in1mLDMSO) $385 2026-05-06 Buy
Arctom HY-15891A GW311616hydrochloride 98.57% 5mg $428 2026-05-26 Buy
Arctom HY-15891A GW311616hydrochloride 98.57% 10mM*1mLinDMSO(Solution) $471 2026-05-26 Buy
Arctom HY-15891A GW311616hydrochloride 98.57% 10mM*1mLinDMSO(Solid+Solvent) $447 2026-05-26 Buy
Arctom HY-15891A GW311616hydrochloride 98.57% 10mg $751 2026-05-26 Buy
Arctom HY-15891A GW311616hydrochloride 98.57% 25mg $1653 2026-05-26 Buy
Axon Medchem Axon2364 GW 311616A 99% 25mg $792 2026-05-19 Buy
Next Last

Properties

storage temp. :2-8°C
solubility :H2O: 24 mg/mL, soluble
form :solid
color :White to yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

GW 311616A is an inhibitor of neutrophil elastase (IC50 = 100 nM). It is selective for neutrophil elastase (IC50 = 22 nM for the human enzyme) over trypsin, cathepsin G, and plasmin (IC50s = >100 μM for all), as well as chymotrypsin and tissue plasminogen activator (IC50s = >3 μM for both), in cell-free assays. GW 311616A (20 μM) inhibits the formation of neutrophil extracellular traps (NETs) induced by phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils. It inhibits intraneutrophil elastase activity in isolated dog blood six hours after administration of a 0.22 mg/kg dose. GW 311616A also inhibits neutrophil elastase in the liver in a mouse model of liver ischemia-reperfusion injury when administered at a dose of 2 mg/kg.

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Suppliers and manufacturers

BOC Sciences ShangHai KenEn Chemical Technology Co., Ltd. SPIRO PHARMA BOC Sciences Shanghai EFE Biological Technology Co., Ltd. Amadis Chemical Company Limited Musechem TargetMol Chemicals Inc. Cckinase, Inc. ChemeGen(Shanghai) Biotechnology Co.,Ltd.