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ChemicalBook >> CAS DataBase List >> LM 22A4

LM 22A4

LM 22A4 price.
  • $62 - $2120
  • Product name: LM 22A4
  • CAS: 37988-18-4
  • MF: C15H21N3O6
  • MW: 339.34
  • EINECS:-0
  • MDL Number:MFCD00382831
  • Synonyms:LM 22A4;N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide;N,N',N''-Tris(beta-hydroxyethyl)trimesamide;1-N,3-N,5-N-TRIS(2-HYDROXYETHYL)BENZENE-1,3,5-TRICARBOXAMIDE;BD2-4;LM 22A4; LM 22A-4;1,3,5-Benzenetricarboxamide, N1,N3,N5-tris(2-hydroxyethyl)-;LM-22A-4,Inhibitor,Trk Receptor,inhibit,LM22A4,LM22A-4,Tropomyosin related kinase receptor,LM22A 4
28 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Azepine
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 5
  • 5mg
  • 25mg
  • 100mg
  • 25
  • 50mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5049
  • Product descriptionLM22A-4
  • Packaging50mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5655
  • Product descriptionLM22A4
  • Packaging25mg
  • Price$394
  • Updated2021-12-16
  • Buy
  • ManufacturerAzepine
  • Product numberAZ0001-0597
  • Product descriptionLM22A4,PotentTrkBagonist 98
  • Packaging1g
  • Price$790
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611629
  • Product descriptionLM22A-4
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611629
  • Product descriptionLM22A-4
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611629
  • Product descriptionLM22A-4
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22082
  • Product descriptionLM22A-4 ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22082
  • Product descriptionLM22A-4 ≥98%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22082
  • Product descriptionLM22A-4 ≥98%
  • Packaging25mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22082
  • Product descriptionLM22A-4 ≥98%
  • Packaging50mg
  • Price$477
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6037
  • Product descriptionLM22A-4 >98.0%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6037
  • Product descriptionLM22A-4 >98.0%
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6037
  • Product descriptionLM22A-4 >98.0%
  • Packaging25mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6037
  • Product descriptionLM22A-4 >98.0%
  • Packaging50mg
  • Price$384
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6037
  • Product descriptionLM22A-4 >98.0%
  • Packaging100mg
  • Price$684
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12077162
  • Product descriptionLM22A4 95+%
  • Packaging10mg
  • Price$63
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5049 LM22A-4 50mg $470 2021-12-16 Buy
ApexBio Technology B5655 LM22A4 25mg $394 2021-12-16 Buy
Azepine AZ0001-0597 LM22A4,PotentTrkBagonist 98 1g $790 2021-12-16 Buy
Biorbyt Ltd orb611629 LM22A-4 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb611629 LM22A-4 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb611629 LM22A-4 1g $1504.5 2021-12-16 Buy
Cayman Chemical 22082 LM22A-4 ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 22082 LM22A-4 ≥98% 10mg $109 2024-03-01 Buy
Cayman Chemical 22082 LM22A-4 ≥98% 25mg $254 2024-03-01 Buy
Cayman Chemical 22082 LM22A-4 ≥98% 50mg $477 2024-03-01 Buy
ChemScene CS-6037 LM22A-4 >98.0% 5mg $66 2021-12-16 Buy
ChemScene CS-6037 LM22A-4 >98.0% 10mg $108 2021-12-16 Buy
ChemScene CS-6037 LM22A-4 >98.0% 25mg $228 2021-12-16 Buy
ChemScene CS-6037 LM22A-4 >98.0% 50mg $384 2021-12-16 Buy
ChemScene CS-6037 LM22A-4 >98.0% 100mg $684 2021-12-16 Buy
Crysdot CD12077162 LM22A4 95+% 10mg $63 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :H2O: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
Water Solubility :H2O: 2mg/mL, clear (warmed)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

LM22A-4 (37988-18-4) is a small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, LM22A-4 caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats.1?Improves respiratory function in a mouse models of Rett syndrome.2

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