Liproxstatin-1
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- $35 - $2134
- Product name: Liproxstatin-1
- CAS: 950455-15-9
- MF: C19H21ClN4
- MW: 340.85
- EINECS:
- MDL Number:MFCD14948691
- Synonyms:Liproxstatin-1;N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine;LIPROXSTATIN-1;LIPROXSTATIN1;CS-1656;N-[(3-chlorophenyl)methyl]spiro[4H-quinoxaline-3,4'-piperidine]-2-amine;Liproxstatin-1 USP/EP/BP;N-[(3-chlorophenyl)methyl]-1'H-spiro[piperidine-4,2'-quinoxaline]-3'-amine;Spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine, N-[(3-chlorophenyl)methyl]-
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 2.00mg
- 10mM(1mLinDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 2mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solution)
- 5mg
- 5.00mg
- 10mM*1mLinDMSO
- 10mM(in 1mL DMSO)
- 10mg
- 10.00mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging1mg
- Price$35
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging2mg
- Price$48
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging5mg
- Price$57
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging10mg
- Price$96
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging25mg
- Price$154
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging50mg
- Price$245
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging100mg
- Price$390
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98%
- Packaging250mg
- Price$661
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYC
- Product descriptionLiproxstatin-1 98
- Packaging200mg
- Price$620
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72353
- Product descriptionLiproxstatin-1 98%
- Packaging1G
- Price$1550
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72353
- Product descriptionLiproxstatin-1 98%
- Packaging100MG
- Price$290
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72353
- Product descriptionLiproxstatin-1 98%
- Packaging25MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72353
- Product descriptionLiproxstatin-1 98%
- Packaging5MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4857EM
- Product descriptionLiproxstatin-1
- Packaging5mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4857EM
- Product descriptionLiproxstatin-1
- Packaging50mg
- Price$758
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120662
- Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
- Packaging1g
- Price$1787
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EAYC | Liproxstatin-1 98% | 1mg | $35 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 2mg | $48 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 5mg | $57 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 10mg | $96 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 25mg | $154 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 50mg | $245 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 100mg | $390 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98% | 250mg | $661 | 2026-05-30 | Buy |
| aablocks | AA01EAYC | Liproxstatin-1 98 | 200mg | $620 | 2026-05-30 | Buy |
| ACHEMBLOCK | S72353 | Liproxstatin-1 98% | 1G | $1550 | 2026-05-27 | Buy |
| ACHEMBLOCK | S72353 | Liproxstatin-1 98% | 100MG | $290 | 2026-05-27 | Buy |
| ACHEMBLOCK | S72353 | Liproxstatin-1 98% | 25MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | S72353 | Liproxstatin-1 98% | 5MG | $45 | 2026-05-27 | Buy |
| AK Scientific | 4857EM | Liproxstatin-1 | 5mg | $201 | 2021-12-16 | Buy |
| AK Scientific | 4857EM | Liproxstatin-1 | 50mg | $758 | 2021-12-16 | Buy |
| Ambeed | A120662 | N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% | 1g | $1787 | 2021-12-16 | Buy |
Properties
Boiling point :581.4±50.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml)
form :powder
pka :9.45±0.40(Predicted)
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.
InChI :InChI=1S/C19H21ClN4/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18/h1-7,12,21,24H,8-11,13H2,(H,22,23)
InChIKey :YAFQFNOUYXZVPZ-UHFFFAOYSA-N
SMILES :N1CCC2(C(NCC3=CC=CC(Cl)=C3)=NC3=C(N2)C=CC=C3)CC1
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml)
form :powder
pka :9.45±0.40(Predicted)
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.
InChI :InChI=1S/C19H21ClN4/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18/h1-7,12,21,24H,8-11,13H2,(H,22,23)
InChIKey :YAFQFNOUYXZVPZ-UHFFFAOYSA-N
SMILES :N1CCC2(C(NCC3=CC=CC(Cl)=C3)=NC3=C(N2)C=CC=C3)CC1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Ferroptosis is a regulated, non-apoptotic form of cell death involving the production of iron-dependent reactive oxygen species (ROS). Glutathione peroxidase 4 (Gpx4) is an essential regulator of ferroptotic cell death, playing a critical role in preventing ROS-induced lipid peroxidation. Liproxstatin-1 is an inhibitor of ferroptosis induced in mouse embryonic fibroblasts (MEFs) by Gpx4 deletion (IC50 = 22 nM). It does not interfere with apoptosis, necroptosis, or necrosis. Liproxstatin-1 also blocks ferroptosis induced by specific ferroptosis inducers, including the glutathioine-depleting agents BSO and erastin and the Gpx4 inhibitor RSL3. It is effective in vivo when administered intraperitoneally, suppressing ferroptosis in Gpx4-/- mice and in a mouse model of ischemia/reperfusion-induced liver injury.More related product prices
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![N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine](https://img.chemicalbook.com/ProductImageEN/2020-1/small/21087427-0db5-42e6-b0e2-1ddb4b1fadf5.png){kind=small}
