PAC1
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- $30 - $2245.7
- Product name: PAC1
- CAS: 315183-21-2
- MF: C23H28N4O2
- MW: 392.49
- EINECS:
- MDL Number:MFCD03302441
- Synonyms:PAC1;4-(Phenylmethyl)-1-piperazineaceticacid[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide;PAC1,4-(PhenylMethyl)-1-piperazineaceticacid[[2-hydroxy-3-(2-propenyl)phenyl]Methylene]hydrazide;4-(Phenylmethyl)-1-piperazineacetic acid 2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide;PAC-1,PAC1;Procaspase activating coMpound 1;(E)-N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide;4-(Phenylmethyl)-1-piperazineacetic acid 2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide PAC-1
65 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- Ark Pharm
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10μg
- 5mg
- 10mg
- 25mg
- 10mM*1mLinDMSO
- 50mg
- 100mg
- 100.00mg
- 250mg
- 50
- 10
- 250.00mg
- 500mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1.00g
- 10mM(in1mLDMSO)
- EvaluationSample
- 10mM(in 1mL DMSO)
- 1000mg
- 10mM(1mLinDMSO)
- 1g
- 2g
- 400μL
- 10mM*1mLinDMSO(Solution)
- 10g
- ManufacturerAK Scientific
- Product numberX5905
- Product descriptionProcaspase-3Activator
- Packaging50mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5905
- Product descriptionProcaspase-3Activator
- Packaging250mg
- Price$696
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging250mg
- Price$600
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging50mg
- Price$150
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging100mg
- Price$250
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging10mM(in1mLDMSO)
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging10mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8177
- Product descriptionPAC-1
- Packaging25mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-13523
- Product descriptionPAC-1 99.88%
- Packaging10mg
- Price$53
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13523
- Product descriptionPAC-1 99.88%
- Packaging25mg
- Price$91
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13523
- Product descriptionPAC-1 99.88%
- Packaging5mg
- Price$33
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13523
- Product descriptionPAC-1 99.88%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$34
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13523
- Product descriptionPAC-1 99.88%
- Packaging10mM*1mLinDMSO(Solution)
- Price$36
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13523
- Product descriptionPAC-1 99.88%
- Packaging100mg
- Price$262
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X5905 | Procaspase-3Activator | 50mg | $165 | 2021-12-16 | Buy |
| AK Scientific | X5905 | Procaspase-3Activator | 250mg | $696 | 2021-12-16 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 250mg | $600 | 2026-05-06 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 50mg | $150 | 2026-05-06 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 100mg | $250 | 2026-05-06 | Buy |
| ApexBio Technology | A8177 | PAC-1 | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 10mM(in1mLDMSO) | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 10mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | A8177 | PAC-1 | 25mg | $80 | 2026-05-06 | Buy |
| Arctom | HY-13523 | PAC-1 99.88% | 10mg | $53 | 2026-05-26 | Buy |
| Arctom | HY-13523 | PAC-1 99.88% | 25mg | $91 | 2026-05-26 | Buy |
| Arctom | HY-13523 | PAC-1 99.88% | 5mg | $33 | 2026-05-26 | Buy |
| Arctom | HY-13523 | PAC-1 99.88% | 10mM*1mLinDMSO(Solid+Solvent) | $34 | 2026-05-26 | Buy |
| Arctom | HY-13523 | PAC-1 99.88% | 10mM*1mLinDMSO(Solution) | $36 | 2026-05-26 | Buy |
| Arctom | HY-13523 | PAC-1 99.88% | 100mg | $262 | 2026-05-26 | Buy |
Properties
Density :1.14
storage temp. :Store at +4°C
solubility :DMSO: ≥10mg/mL
form :solid
pka :8.82±0.40(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol must be stored under inert gas at -80°C and will be stable for up to 2 months.
InChI :1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+
InChIKey :YQNRVGJCPCNMKT-LFVJCYFKSA-N
SMILES :Oc1c(CC=C)cccc1\C=N\NC(=O)CN2CCN(CC2)Cc3ccccc3
storage temp. :Store at +4°C
solubility :DMSO: ≥10mg/mL
form :solid
pka :8.82±0.40(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol must be stored under inert gas at -80°C and will be stable for up to 2 months.
InChI :1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+
InChIKey :YQNRVGJCPCNMKT-LFVJCYFKSA-N
SMILES :Oc1c(CC=C)cccc1\C=N\NC(=O)CN2CCN(CC2)Cc3ccccc3
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||
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Description
PAC 1 is a procaspase-activating compound, which in turn produces caspase-3 (EC50 = 0.22 μM). PAC 1 also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). This compound is a proapoptotic, inducing apoptosis in both cancerous and non-cancerous cell lines. The induction of apoptosis is dependent on the concentration of procaspase-3 (IC50 values anre 0.003-1.41 and 5.02=9.98 μM, respectively).Related product price
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