PD 166285
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- $118 - $2000
- Product name: PD 166285
- CAS: 212391-63-4
- MF: C26H29Cl4N5O2
- MW: 585.37
- EINECS:
- MDL Number:MFCD18086890
- Synonyms:6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one Hydrochloride;PD 166285;6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-onedihydrochloride;PD 166285 dihydrochloride;6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylaMino-ethoxy)-phenylaMino]-8-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one hydrochloride;6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimi;6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylaMino)ethoxy]phenyl]aMino]-8-Methylpyrido[2,3-d]pyriMidin-7(8H)-one;PD 166285 - CAS 212391-63-4 - Calbiochem
25 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 1
- 2mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA003THI
- Product descriptionPD 166285 2HCl 98%byHPLC
- Packaging50mg
- Price$858
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003THI
- Product descriptionPD 166285 2HCl 98%byHPLC
- Packaging25mg
- Price$522
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003THI
- Product descriptionPD 166285 2HCl 98%byHPLC
- Packaging10mg
- Price$270
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003THI
- Product descriptionPD 166285 2HCl 98%byHPLC
- Packaging5mg
- Price$178
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number4197CR
- Product description6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
- Packaging2mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4197CR
- Product description6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
- Packaging5mg
- Price$387
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000178
- Product descriptionPD-166285 95.00%
- Packaging5MG
- Price$786.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000178
- Product descriptionPD-166285 95.00%
- Packaging50MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging50mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging2mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging25mg
- Price$1250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC21466
- Product descriptionPD166285 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC21466
- Product descriptionPD166285 >98%
- Packaging250mg
- Price$1000
- Updated2026-05-24
- Buy
- ManufacturerDC Chemicals
- Product numberDC21466
- Product descriptionPD166285 >98%
- Packaging1g
- Price$2000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003THI | PD 166285 2HCl 98%byHPLC | 50mg | $858 | 2026-05-28 | Buy |
| aablocks | AA003THI | PD 166285 2HCl 98%byHPLC | 25mg | $522 | 2026-05-28 | Buy |
| aablocks | AA003THI | PD 166285 2HCl 98%byHPLC | 10mg | $270 | 2026-05-28 | Buy |
| aablocks | AA003THI | PD 166285 2HCl 98%byHPLC | 5mg | $178 | 2026-05-28 | Buy |
| AK Scientific | 4197CR | 6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride | 2mg | $239 | 2021-12-16 | Buy |
| AK Scientific | 4197CR | 6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride | 5mg | $387 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000178 | PD-166285 95.00% | 5MG | $786.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000178 | PD-166285 95.00% | 50MG | $1963.5 | 2021-12-16 | Buy |
| Biosynth | FP26776 | PD 166285 | 50mg | $600 | 2021-12-16 | Buy |
| Biosynth | FP26776 | PD 166285 | 2mg | $140 | 2021-12-16 | Buy |
| Biosynth | FP26776 | PD 166285 | 5mg | $250 | 2021-12-16 | Buy |
| Biosynth | FP26776 | PD 166285 | 25mg | $1250 | 2021-12-16 | Buy |
| Biosynth | FP26776 | PD 166285 | 10mg | $400 | 2021-12-16 | Buy |
| DC Chemicals | DC21466 | PD166285 >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC21466 | PD166285 >98% | 250mg | $1000 | 2026-05-24 | Buy |
| DC Chemicals | DC21466 | PD166285 >98% | 1g | $2000 | 2021-12-16 | Buy |
Properties
Melting point :239-242C
storage temp. :Desiccate at RT
solubility :DMSO, Methanol
form :Pale yellow solid
color :Yellow
Stability :Hygroscopic
InChIKey :NADLBPWBFGTESN-UHFFFAOYSA-N
SMILES :C1(NC2=CC=C(OCCN(CC)CC)C=C2)=NC=C2C=C(C3=C(Cl)C=CC=C3Cl)C(=O)N(C)C2=N1.Cl.Cl
storage temp. :Desiccate at RT
solubility :DMSO, Methanol
form :Pale yellow solid
color :Yellow
Stability :Hygroscopic
InChIKey :NADLBPWBFGTESN-UHFFFAOYSA-N
SMILES :C1(NC2=CC=C(OCCN(CC)CC)C=C2)=NC=C2C=C(C3=C(Cl)C=CC=C3Cl)C(=O)N(C)C2=N1.Cl.Cl
Safety Information
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Description
PD 166285 is a potent inhibitor of the tyrosine kinases c-Src, Flg (fibroblast growth factor receptor 1, FGFR1), and PDGFRβ (platelet-derived growth factor receptor β) (IC50 values are 8.4, 39.3 and 98.3 nM respectively). PD 166285 also inhibits the checkpoint kinases Wee1 and MYT1 (Myt1), abolishes Cdc2 phosphorylation in numerous tumor cell lines, and abrogates the G2 checkpoint. PD 166285 is an RTK inhibitor with broad-spectrum properties and displays anti-angiogenic activity and anti-tumor efficacy when used with PDT (photodynamic therapy). PD 166285 is an inhibitor of EGFR.More related product prices
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