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ChemicalBook >> CAS DataBase List >> PF-6274484

PF-6274484

$34 - $4092
Product name: PF-6274484
CAS: 1035638-91-5
MF: C18H14ClFN4O2
MW: 372.78
EINECS:
MDL Number:MFCD30182370
Synonyms:PF-6274484;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-;PF-6274484 >=98% (HPLC);oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor;N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide;PF-6274484, 10 mM in DMSO

Price23 Properties Safety Information Description

23 prices

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Brand

ACHEMBLOCK
AK Scientific
Cayman Chemical
Chemenu
DC Chemicals
TRC

Package

1mg
5mg
10mg
50mg
100MG
250MG
1G

ManufacturerACHEMBLOCK
Product numberX185432
Product descriptionPF 6274484 95%
Packaging100MG
Price$225
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberX185432
Product descriptionPF 6274484 95%
Packaging250MG
Price$450
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberX185432
Product descriptionPF 6274484 95%
Packaging1G
Price$1170
Updated2026-05-25
Buy

ManufacturerAK Scientific
Product number8711DW
Product descriptionN-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
Packaging5mg
Price$209
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number8711DW
Product descriptionN-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
Packaging10mg
Price$302
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number22698
Product descriptionPF-6274484 ≥98%
Packaging1mg
Price$34
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22698
Product descriptionPF-6274484 ≥98%
Packaging1mg
Price$38
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number22698
Product descriptionPF-6274484 ≥98%
Packaging5mg
Price$100
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22698
Product descriptionPF-6274484 ≥98%
Packaging5mg
Price$110
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number22698
Product descriptionPF-6274484 ≥98%
Packaging10mg
Price$166
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22698
Product descriptionPF-6274484 ≥98%
Packaging10mg
Price$183
Updated2026-04-30
Buy

ManufacturerChemenu
Product numberCM456257
Product descriptionN-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+
Packaging10mg
Price$903
Updated2026-05-20
Buy

ManufacturerChemenu
Product numberCM456257
Product descriptionN-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+
Packaging10mg
Price$903
Updated2026-05-26
Buy

ManufacturerChemenu
Product numberCM456257
Product descriptionN-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+
Packaging50mg
Price$2484
Updated2026-05-20
Buy

ManufacturerChemenu
Product numberCM456257
Product descriptionN-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+
Packaging50mg
Price$2484
Updated2026-05-26
Buy

ManufacturerChemenu
Product numberCM456257
Product descriptionN-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+
Packaging100mg
Price$4092
Updated2026-05-20
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
ACHEMBLOCK	X185432	PF 6274484 95%	100MG	$225	2026-05-25	Buy
ACHEMBLOCK	X185432	PF 6274484 95%	250MG	$450	2026-05-25	Buy
ACHEMBLOCK	X185432	PF 6274484 95%	1G	$1170	2026-05-25	Buy
AK Scientific	8711DW	N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide	5mg	$209	2021-12-16	Buy
AK Scientific	8711DW	N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide	10mg	$302	2021-12-16	Buy
Cayman Chemical	22698	PF-6274484 ≥98%	1mg	$34	2024-03-01	Buy
Cayman Chemical	22698	PF-6274484 ≥98%	1mg	$38	2026-04-30	Buy
Cayman Chemical	22698	PF-6274484 ≥98%	5mg	$100	2024-03-01	Buy
Cayman Chemical	22698	PF-6274484 ≥98%	5mg	$110	2026-04-30	Buy
Cayman Chemical	22698	PF-6274484 ≥98%	10mg	$166	2024-03-01	Buy
Cayman Chemical	22698	PF-6274484 ≥98%	10mg	$183	2026-04-30	Buy
Chemenu	CM456257	N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+	10mg	$903	2026-05-20	Buy
Chemenu	CM456257	N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+	10mg	$903	2026-05-26	Buy
Chemenu	CM456257	N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+	50mg	$2484	2026-05-20	Buy
Chemenu	CM456257	N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+	50mg	$2484	2026-05-26	Buy
Chemenu	CM456257	N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 95%+	100mg	$4092	2026-05-20	Buy

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Properties

storage temp. :Store at -20°C
solubility :DMF: 33 mg/ml; DMSO: 25 mg/ml
form :A crystalline solid
color :Light yellow to orange
InChI :1S/C19H16ClFN4O/c1-4-11(2)24-17-8-13-16(9-18(17)26-3)22-10-23-19(13)25-12-5-6-15(21)14(20)7-12/h4-10,24H,1-2H2,3H3,(H,22,23,25)
InChIKey :DTMQCGFVWWBONL-UHFFFAOYSA-N
SMILES :FC(C=C1)=C(Cl)C=C1NC2=NC=NC3=CC(OC)=C(NC(C=C)=O)C=C32

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

PF-6274484 is an irreversible EGFR kinase inhibitor that covalently reacts with active-site cysteine residues in the ATP binding pocket. PF-6274484 inhibits autophosphorylation of both wild type and mutant EGFR in tumor cells with IC50 values of 5.8 nM and 6.6 nM, respectively.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$34.00 /2mg
PF-6274484 CAS:1035638-91-5

ATK CHEMICAL COMPANY LIMITED

Aladdin Scientific Nanjing Dulai Biotechnology Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd BOC Sciences

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PF-6274484

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