PI-103
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- $28 - $2200
- Product name: PI-103
- CAS: 371935-74-9
- MF: C19H16N4O3
- MW: 348.36
- EINECS:
- MDL Number:MFCD11983145
- Synonyms:Phenol, 3-[4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyriMidin-2-yl]-;3-(4-Morpholinopyrido[3',2':4,5] furo[3,2-d]pyriMidin-2-yl)phenol;PI 3-Kinase Inhibitor (PI-103) B-0303;PI-103, Free Base, >99%;PI-103HydrochlorideSalt;3-[4-(4-Morpholinylpyrido[3',2',4,5]furo[3,2-d]pyrimidin-2-yl]phenol;3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol hydrochloride;3-[4-(4-Morpholinylpyrido[3',2',4,5]furo[3,2-d]pyrimidin-2-yl]phenol PI 103
45 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1
- 25mg
- 200mg
- 50
- 500mg
- 1g
- 10
- 10mM(in 1mL DMSO)
- 1mg
- 1unit
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1065-M005
- Product descriptionPI103 ≥95%
- Packaging5mg
- Price$157
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1065-M010
- Product descriptionPI103 ≥95%
- Packaging10mg
- Price$248
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1065-M050
- Product descriptionPI103 ≥95%
- Packaging50mg
- Price$486
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7432
- Product descriptionPI-103
- Packaging1mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7432
- Product descriptionPI-103
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7432
- Product descriptionPI-103
- Packaging100mg
- Price$365
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7432
- Product descriptionPI-103
- Packaging250mg
- Price$667
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA344838
- Product description3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 98+%
- Packaging5mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA344838
- Product description3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 98+%
- Packaging10mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA344838
- Product description3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 98+%
- Packaging50mg
- Price$281
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000189
- Product descriptionPI-103 95.00%
- Packaging1MG
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000189
- Product descriptionPI-103 95.00%
- Packaging5MG
- Price$747.4
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2067
- Product descriptionPI-103
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2067
- Product descriptionPI-103
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2067
- Product descriptionPI-103
- Packaging10mM(in 1mL DMSO)
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2067
- Product descriptionPI-103
- Packaging25mg
- Price$240
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1065-M005 | PI103 ≥95% | 5mg | $157 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1065-M010 | PI103 ≥95% | 10mg | $248 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1065-M050 | PI103 ≥95% | 50mg | $486 | 2021-12-16 | Buy |
| AK Scientific | X7432 | PI-103 | 1mg | $96 | 2021-12-16 | Buy |
| AK Scientific | X7432 | PI-103 | 5mg | $120 | 2021-12-16 | Buy |
| AK Scientific | X7432 | PI-103 | 100mg | $365 | 2021-12-16 | Buy |
| AK Scientific | X7432 | PI-103 | 250mg | $667 | 2021-12-16 | Buy |
| Ambeed | A344838 | 3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 98+% | 5mg | $66 | 2021-12-16 | Buy |
| Ambeed | A344838 | 3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 98+% | 10mg | $111 | 2021-12-16 | Buy |
| Ambeed | A344838 | 3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 98+% | 50mg | $281 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000189 | PI-103 95.00% | 1MG | $430 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000189 | PI-103 95.00% | 5MG | $747.4 | 2021-12-16 | Buy |
| ApexBio Technology | A2067 | PI-103 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A2067 | PI-103 | 5mg | $84 | 2021-12-16 | Buy |
| ApexBio Technology | A2067 | PI-103 | 10mM(in 1mL DMSO) | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A2067 | PI-103 | 25mg | $240 | 2021-12-16 | Buy |
Properties
Density :1.409±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 40 mg/ml)
form :White solid
pka :9.06±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 40 mg/ml)
form :White solid
pka :9.06±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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Description
PI-103 is a cell-permeable pyridinylfuranopyrimidine compound that acts as an ATP-competitive inhibitor of DNA-PK, PI 3-kinase (Class IA), and FRAP (mTOR) complex 1 and 2. Studies suggest that PI-103 can induce apoptosis and an arrest in the cell cycle by inhibition of the aforementioned proteins. When PI-103 is combined with rapamycin, a prototypic mTORC1 inhibitor, synergistic suppression of AKT and ribosomal S6 protein phosphorylation are observed. In addition, PI-103 has been seen to have nominal effects inhibiting basal Na+ transport, but is very effective in abolishing insulin-induced Na+ absorption in the nephron.More related product prices
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