Poziotinib (HM781-36B)
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- $26 - $1342
- Product name: Poziotinib (HM781-36B)
- CAS: 1092364-38-9
- MF: C23H21Cl2FN4O3
- MW: 491.34
- EINECS:
- MDL Number:MFCD28044290
- Synonyms:1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one;UNII-OEI6OOU6IK;1-(4-((4-((3,4-dichloro-2-fluorophenyl)aMino)-7- Methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one;1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one;poziotinib(HM-78136B);NOV120101;1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Poziotinib;HM781-36B)
20 prices
                Selected condition:
                            Brand
                                - AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
                                    
                                - 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2856DC
- Product descriptionPoziotinib
- Packaging1g
- Price$1342
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5827
- Product descriptionPoziotinib
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5827
- Product descriptionPoziotinib
- Packaging10mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5827
- Product descriptionPoziotinib
- Packaging50mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP161454
- Product descriptionPoziotinib
- Packaging1mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP161454
- Product descriptionPoziotinib
- Packaging2mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP161454
- Product descriptionPoziotinib
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP161454
- Product descriptionPoziotinib
- Packaging10mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP161454
- Product descriptionPoziotinib
- Packaging25mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22437
- Product descriptionPoziotinib ≥95%
- Packaging1mg
- Price$26
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22437
- Product descriptionPoziotinib ≥95%
- Packaging5mg
- Price$85
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22437
- Product descriptionPoziotinib ≥95%
- Packaging10mg
- Price$143
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22437
- Product descriptionPoziotinib ≥95%
- Packaging25mg
- Price$228
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3942
- Product descriptionPoziotinib 99.97%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3942
- Product descriptionPoziotinib 99.97%
- Packaging50mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3942
- Product descriptionPoziotinib 99.97%
- Packaging100mg
- Price$708
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy | 
|---|---|---|---|---|---|---|
| AK Scientific | 2856DC | Poziotinib | 1g | $1342 | 2021-12-16 | Buy | 
| ApexBio Technology | B5827 | Poziotinib | 5mg | $50 | 2021-12-16 | Buy | 
| ApexBio Technology | B5827 | Poziotinib | 10mg | $110 | 2021-12-16 | Buy | 
| ApexBio Technology | B5827 | Poziotinib | 50mg | $390 | 2021-12-16 | Buy | 
| Biosynth Carbosynth | BP161454 | Poziotinib | 1mg | $60 | 2021-12-16 | Buy | 
| Biosynth Carbosynth | BP161454 | Poziotinib | 2mg | $110 | 2021-12-16 | Buy | 
| Biosynth Carbosynth | BP161454 | Poziotinib | 5mg | $150 | 2021-12-16 | Buy | 
| Biosynth Carbosynth | BP161454 | Poziotinib | 10mg | $250 | 2021-12-16 | Buy | 
| Biosynth Carbosynth | BP161454 | Poziotinib | 25mg | $550 | 2021-12-16 | Buy | 
| Cayman Chemical | 22437 | Poziotinib ≥95% | 1mg | $26 | 2024-03-01 | Buy | 
| Cayman Chemical | 22437 | Poziotinib ≥95% | 5mg | $85 | 2024-03-01 | Buy | 
| Cayman Chemical | 22437 | Poziotinib ≥95% | 10mg | $143 | 2024-03-01 | Buy | 
| Cayman Chemical | 22437 | Poziotinib ≥95% | 25mg | $228 | 2024-03-01 | Buy | 
| ChemScene | CS-3942 | Poziotinib 99.97% | 5mg | $96 | 2021-12-16 | Buy | 
| ChemScene | CS-3942 | Poziotinib 99.97% | 50mg | $468 | 2021-12-16 | Buy | 
| ChemScene | CS-3942 | Poziotinib 99.97% | 100mg | $708 | 2021-12-16 | Buy | 
Properties
                        
                        Melting point :187 - 190° C
Boiling point :629.7±55.0 °C(Predicted)
Density :1.409±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
pka :5.35±0.30(Predicted)
form :Solid
color :White to Pale Beige
InChIKey :LPFWVDIFUFFKJU-UHFFFAOYSA-N
SMILES :C(N1CCC(OC2C(OC)=CC3C(C=2)=C(NC2=CC=C(Cl)C(Cl)=C2F)N=CN=3)CC1)(=O)C=C
CAS DataBase Reference :1092364-38-9
                        
                    
                Boiling point :629.7±55.0 °C(Predicted)
Density :1.409±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
pka :5.35±0.30(Predicted)
form :Solid
color :White to Pale Beige
InChIKey :LPFWVDIFUFFKJU-UHFFFAOYSA-N
SMILES :C(N1CCC(OC2C(OC)=CC3C(C=2)=C(NC2=CC=C(Cl)C(Cl)=C2F)N=CN=3)CC1)(=O)C=C
CAS DataBase Reference :1092364-38-9
Safety Information
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Description
Poziotinib (HM781-36B) is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Phase 2.Related product price
- Canertinib
 $29-1828
- AZD8931
 $44-35050
- IPI 145
 $68-2550
Suppliers and manufacturers
                    
                    
                    
                    
                    
                    
                    
                    
                        
                        ATK CHEMICAL COMPANY LIMITED  
                    
                    
                        
                        TianYuan Pharmaceutical CO.,LTD  
                    
                    
                        
                        Shenzhen Excellent Biotech Co., Ltd.  
                    
                    
                        
                        Jurong Coupling Biotechnology Co., Ltd.  
                    
                    
                        
                        Hubei Ipure Biology Co., Ltd  
                    
                    
                        
                        HANGZHOU CLAP TECHNOLOGY CO.,LTD  
                    
                    
                        
                        Shanghai UCHEM Inc.  
                    
                
             
                    
 
                    
                    

 
        
 
                                 
                                