SB 225002
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- $12 - $2180
- Product name: SB 225002
- CAS: 182498-32-4
- MF: C13H10BrN3O4
- MW: 352.14
- EINECS:
- MDL Number:MFCD00954637
- Synonyms:SB 225002;N-(2-HYDROXY-4-NITROPHENYL)-N'-(2-BROMOPHENYL)UREA;N-(2-BROMOPHENYL)-N'-(2-HYDROXY-4-NITROPHENYL)UREA;1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea;SB 225002 - CAS 182498-32-4 - Calbiochem;SB-225002;SB 225002;Urea, N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-;SB 225002 USP/EP/BP
84 prices
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
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- Matrix Scientific
- Sigma-Aldrich
- Synthonix
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
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- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 10
- 200mg
- 250mg
- 250.00mg
- 50
- 10mM(in1mLDMSO)
- 500mg
- 1g
- 5G
- 10g
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 99%(HPLC)
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 99%(HPLC)
- Packaging5mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 99%(HPLC)
- Packaging10mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 99%(HPLC)
- Packaging25mg
- Price$25
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 99%(HPLC)
- Packaging50mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 99%(HPLC)
- Packaging100mg
- Price$70
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 >97%
- Packaging250mg
- Price$100
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0023UQ
- Product descriptionSB-225002 >97%
- Packaging1g
- Price$230
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU138617
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 97%
- Packaging1G
- Price$310
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU138617
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 97%
- Packaging5G
- Price$935
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU138617
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 97%
- Packaging250MG
- Price$135
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2703AH
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
- Packaging1g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2703AH
- Product description1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
- Packaging10g
- Price$1747
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging1g
- Price$2180
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging50mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA149514
- Product descriptionSB 225002 98+%
- Packaging10mg
- Price$67
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0023UQ | SB-225002 99%(HPLC) | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 99%(HPLC) | 5mg | $14 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 99%(HPLC) | 10mg | $17 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 99%(HPLC) | 25mg | $25 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 99%(HPLC) | 50mg | $42 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 99%(HPLC) | 100mg | $70 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 >97% | 250mg | $100 | 2026-05-28 | Buy |
| aablocks | AA0023UQ | SB-225002 >97% | 1g | $230 | 2026-05-28 | Buy |
| ACHEMBLOCK | U138617 | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 97% | 1G | $310 | 2026-05-27 | Buy |
| ACHEMBLOCK | U138617 | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 97% | 5G | $935 | 2026-05-27 | Buy |
| ACHEMBLOCK | U138617 | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 97% | 250MG | $135 | 2026-05-27 | Buy |
| AK Scientific | 2703AH | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea | 1g | $370 | 2021-12-16 | Buy |
| AK Scientific | 2703AH | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea | 10g | $1747 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 1g | $2180 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 50mg | $115 | 2021-12-16 | Buy |
| Ambeed | A149514 | SB 225002 98+% | 10mg | $67 | 2021-12-16 | Buy |
Properties
Boiling point :401.6±45.0 °C(Predicted)
Density :1.793±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble to 100mM in DMSO and to 50mM in ethanol
form :Yellow solid
pka :5.29±0.10(Predicted)
color :white to beige
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C13H10BrN3O4/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17(20)21)7-12(11)18/h1-7,18H,(H2,15,16,19)
InChIKey :MQBZVUNNWUIPMK-UHFFFAOYSA-N
SMILES :Brc1c(cccc1)NC(=O)Nc2c(cc(cc2)[N+](=O)[O-])O
CAS DataBase Reference :182498-32-4
Density :1.793±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble to 100mM in DMSO and to 50mM in ethanol
form :Yellow solid
pka :5.29±0.10(Predicted)
color :white to beige
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C13H10BrN3O4/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17(20)21)7-12(11)18/h1-7,18H,(H2,15,16,19)
InChIKey :MQBZVUNNWUIPMK-UHFFFAOYSA-N
SMILES :Brc1c(cccc1)NC(=O)Nc2c(cc(cc2)[N+](=O)[O-])O
CAS DataBase Reference :182498-32-4
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and growth related oncogene α (Gro-α; CXCL1). IL-8 and Gro-α are pro-inflammatory CXC chemokines that act as chemoattractants, especially for neutrophils, and promote angiogenesis. SB 225002 is a selective non-peptide inhibitor of CXCR2, inhibiting IL-8 binding to CXCR2 with an IC50 value of 22 nM. SB225002 inhibits neutrophil chemotaxis in response to IL-8 in vitro (IC50 = 20 nM) and blocks neutrophil margination induced by IL-8 in vivo (IC50 = 30 nM). Similarly, SB 225002 reduces neutrophil influx, the production of inflammatory mediators, and tissue damage in TNBS-induced colitis in mice.Related product price
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