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ChemicalBook >> CAS DataBase List >> SCH772984

SCH772984

SCH772984 price.
  • $37 - $2620
  • Product name: SCH772984
  • CAS: 942183-80-4
  • MF: C33H33N9O2
  • MW: 587.67
  • EINECS:1592732-453-0
  • MDL Number:MFCD11878503
  • Synonyms:SCH772984;SCH772984/SCH-772984;(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide;(R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide;(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide SCH772984;(R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-;SCH772984, >=98%;(R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indaz
Price87 Properties Safety Information Description
87 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • J&W Pharmlab
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 2mg
  • 5mg
  • 10mg
  • 1mg
  • 10mM*1mLinDMSO
  • 10mM(in1mLDMSO)
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1G
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98%
  • Packaging10mg
  • Price$125
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 95%
  • Packaging25mg
  • Price$307
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide ≥98%
  • Packaging50mg
  • Price$583
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 95%
  • Packaging100mg
  • Price$744
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98%
  • Packaging5mg
  • Price$83
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98%
  • Packaging2mg
  • Price$61
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00394M
  • Product description(3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98%
  • Packaging1mg
  • Price$41
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10380
  • Product descriptionSCH772984 98%
  • Packaging5MG
  • Price$55
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10380
  • Product descriptionSCH772984 98%
  • Packaging100MG
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10380
  • Product descriptionSCH772984 98%
  • Packaging1G
  • Price$1250
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10380
  • Product descriptionSCH772984 98%
  • Packaging25MG
  • Price$195
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5640
  • Product descriptionSCH772984
  • Packaging100mg
  • Price$1660
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA378792
  • Product description(R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+%
  • Packaging1g
  • Price$1980
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA378792
  • Product description(R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+%
  • Packaging100mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA378792
  • Product description(R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+%
  • Packaging250mg
  • Price$792
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA378792
  • Product description(R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+%
  • Packaging10mg
  • Price$161
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98% 10mg $125 2026-05-28 Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 95% 25mg $307 2026-05-28 Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide ≥98% 50mg $583 2026-05-28 Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 95% 100mg $744 2026-05-28 Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98% 5mg $83 2026-05-28 Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98% 2mg $61 2026-05-28 Buy
aablocks AA00394M (3R)-1-[2-Oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide 98% 1mg $41 2026-05-28 Buy
ACHEMBLOCK 10380 SCH772984 98% 5MG $55 2026-05-27 Buy
ACHEMBLOCK 10380 SCH772984 98% 100MG $550 2026-05-27 Buy
ACHEMBLOCK 10380 SCH772984 98% 1G $1250 2026-05-27 Buy
ACHEMBLOCK 10380 SCH772984 98% 25MG $195 2026-05-27 Buy
AK Scientific SYN5640 SCH772984 100mg $1660 2021-12-16 Buy
Ambeed A378792 (R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+% 1g $1980 2021-12-16 Buy
Ambeed A378792 (R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+% 100mg $660 2021-12-16 Buy
Ambeed A378792 (R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+% 250mg $792 2021-12-16 Buy
Ambeed A378792 (R)-1-(2-Oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide 98+% 10mg $161 2021-12-16 Buy
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Properties

Melting point :>214°C (dec.)
Boiling point :857.3±65.0 °C(Predicted)
Density :1.353±0.06(20.0000℃)
storage temp. :Refrigerator
solubility :DMSO (Slightly)
pka :12.05±0.40(Predicted)
form :Solid
color :Pale Yellow
InChIKey :HDAJDNHIBCDLQF-RUZDIDTESA-N
SMILES :N1(CC(=O)N2CCN(C3=CC=C(C4=NC=CC=N4)C=C3)CC2)CC[C@@H](C(NC2C=CC3=C(C=2)C(C2C=CN=CC=2)=NN3)=O)C1
CAS DataBase Reference :942183-80-4

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The extracellular regulated kinases 1 and 2 (ERK1/2) are functionally redundant kinases activated by a variety of growth factors and mitogens. SCH 772984 is a potent inhibitor of ERK1 and ERK2 (IC50s = 4 and 1 nM, respectively). It is highly selective, with only seven kinases of 300 tested showing more than 50% inhibition at a concentration of 1 μM. SCH 772984 has nanomolar cytotoxicity in tumor cells with mutations in BRAF, NRAS, or KRAS. It is effective in vivo, inducing regression of xenograft tumors in mice. SCH 772984 displays slow binding kinetics, binding to a novel binding pocket in inactive ERK isoforms.

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Suppliers and manufacturers

career henan chemical co
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